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吲哚菁绿荧光成像在直肠癌患者机器人辅助保肛手术中的应用价值。

Utility of indocyanine-green fluorescent imaging during robot-assisted sphincter-saving surgery on rectal cancer patients.

作者信息

Kim Jin C, Lee Jong L, Yoon Yong S, Alotaibi Abdulrahman M, Kim Jihun

机构信息

Department of Surgery, University of Ulsan College of Medicine and Asan Medical Centre, Seoul, Korea.

Department of Pathology, University of Ulsan College of Medicine and Asan Medical Centre, Seoul, Korea.

出版信息

Int J Med Robot. 2016 Dec;12(4):710-717. doi: 10.1002/rcs.1710. Epub 2015 Oct 21.

DOI:10.1002/rcs.1710
PMID:26486376
Abstract

BACKGROUND

There have been few studies describing the use of indocyanine green (ICG) fluorescent imaging during robot-assisted (RA) sphincter-saving operations (SSOs) and assessing its potential role in reducing anastomotic leak (AL).

METHODS

A consecutive cohort of 436 rectal cancer patients who underwent curative RA SSOs were prospectively enrolled during 2010-2014, including 123 patients with ICG imaging (ICG group) and 313 patients without ICG imaging (ICG group).

RESULTS

ICG imaging appeared to be helpful in identifying competent perfusion of the bowel adjacent to the anastomosis in 13 patients (10.6%) who might be susceptible to bowel ischaemia, including restrictive mesocolon. AL was remarkably greater in the ICG group compared with the ICG group (5.4% vs 0.8%; p = 0.031).

CONCLUSIONS

ICG imaging during RA SSO provides accurate real-time knowledge of the perfusion status at or near the anastomosis, specifically reducing AL in patients who may incur bowel ischaemia. Copyright © 2015 John Wiley & Sons, Ltd.

摘要

背景

很少有研究描述在机器人辅助保留括约肌手术(SSO)中使用吲哚菁绿(ICG)荧光成像,并评估其在减少吻合口漏(AL)方面的潜在作用。

方法

2010年至2014年期间,前瞻性纳入了连续436例行根治性机器人辅助SSO的直肠癌患者,其中123例患者进行了ICG成像(ICG组),313例患者未进行ICG成像(非ICG组)。

结果

ICG成像似乎有助于识别13例(10.6%)可能易发生肠缺血(包括结肠系膜狭窄)的吻合口附近肠管的有效灌注情况。ICG组的AL明显高于非ICG组(5.4%对0.8%;p = 0.031)。

结论

机器人辅助SSO期间的ICG成像可提供吻合口处或其附近灌注状态的准确实时信息,尤其可减少可能发生肠缺血患者的AL。版权所有© 2015约翰·威利父子有限公司。

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