MMWR Morb Mortal Wkly Rep. 2015 Oct 30;64(42):1190-3. doi: 10.15585/mmwr.mm6442a2.
During 2000–2011, passive surveillance for legionellosis in the United States demonstrated a 249% increase in crude incidence, although little was known about the clinical course and method of diagnosis. In 2011, a system of active, population-based surveillance for legionellosis was instituted through CDC’s Active Bacterial Core surveillance (ABCs) program. Overall disease rates were similar in both the passive and active systems, but more complete demographic information and additional clinical and laboratory data were only available from ABCs. ABCs data during 2011–2013 showed that approximately 44% of patients with legionellosis required intensive care, and 9% died. Disease incidence was higher among blacks than whites and was 10 times higher in New York than California. Laboratory data indicated a reliance on urinary antigen testing, which only detects Legionella pneumophila serogroup 1 (Lp1). ABCs data highlight the severity of the disease, the need to better understand racial and regional differences, and the need for better diagnostic testing to detect infections.
在 2000 年至 2011 年间,美国对军团病的被动监测显示粗发病率增长了 249%,尽管对其临床过程和诊断方法知之甚少。2011 年,通过疾病预防控制中心的主动细菌核心监测(ABCs)计划建立了一个主动、基于人群的军团病监测系统。被动和主动系统的总疾病率相似,但只有 ABCs 提供了更完整的人口统计学信息以及更多的临床和实验室数据。2011 年至 2013 年的 ABCs 数据显示,约有 44%的军团病患者需要重症监护,9%的患者死亡。黑人的发病率高于白人,而纽约的发病率比加利福尼亚高 10 倍。实验室数据表明,人们依赖于尿抗原检测,而这种检测只能检测出嗜肺军团菌血清群 1(Lp1)。ABCs 的数据突出了疾病的严重性,需要更好地了解种族和地区差异,以及需要更好的诊断检测来发现感染。