Spedo Carina T, Frndak Seth E, Marques Vanessa D, Foss Maria P, Pereira Danilo A, Carvalho Lucas de F, Guerreiro Carlos T, Conde Rodrigo M, Fusco Tatiana, Pereira Ana J, Gaino Silvana B, Garcia Ricardo B, Benedict Ralph H B, Barreira Amilton A
a Department of Neuroscience and Behavior Sciences , Ribeirão Preto Medical School, University of São Paulo (FMRP-USP) , São Paulo , Brazil.
b Departments of Neurology and Psychiatry, School of Medicine and Biomedical Sciences , University at Buffalo, State University of New York , Buffalo , NY , USA.
Clin Neuropsychol. 2015;29(6):836-46. doi: 10.1080/13854046.2015.1093173. Epub 2015 Oct 29.
To investigate the reliability and validity of a Brazilian-Portuguese adaptation of the Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS).
A Brazilian sample of 58 multiple sclerosis (MS) patients and 58 healthy controls (HC) were administered the Brazilian-Portuguese BICAMS test battery, comprising the Symbol Digit Modalities Test (SDMT), California Verbal Learning Test Second Edition (CVLT2), and the Brief Visuospatial Memory Test Revised (BVMTR). Mean differences between groups on BICAMS tests were assessed using analysis of covariance (ANCOVA), controlling for age, gender, education, anxiety, and depression. Test-retest data were obtained from 49 of the MS patients, two weeks after the initial assessment.
The MS patient group scored significantly lower on all BICAMS tests (CVLT2 F1,110 = 28.99, p < .001; BVMTR F1,110 = 7.77, p < .01; SDMT F1,110 = 21.09, p < .001). Mixed-factor ANCOVAs tested differences in learning curves across trials for CVLT2 and BVMTR. HCs had significantly steeper learning curves on both CVLT2 (F1,111 = 10.82, p < .01) and BVMTR (F1,110 = 7.816, p < .01). These findings support diagnostic validity of the Brazilian-Portuguese adaptation. Test-retest reliability was satisfactory for SDMT, CVLT2, and BVMTR (.86, .84, and .77, respectively).
The results suggest that this Brazilian version of the BICAMS will be a valid and reliable measure once complete normative data become available.
探讨巴西葡萄牙语版多发性硬化症简短国际认知评估量表（BICAMS）的信度和效度。
对58例巴西多发性硬化症（MS）患者和58例健康对照者（HC）进行巴西葡萄牙语版BICAMS测试组合，包括符号数字模式测验（SDMT）、加利福尼亚言语学习测验第二版（CVLT2）和修订版简短视觉空间记忆测验（BVMTR）。使用协方差分析（ANCOVA）评估BICAMS测试中两组之间的平均差异，并控制年龄、性别、教育程度、焦虑和抑郁因素。重测数据来自49例MS患者，在首次评估两周后获取。
MS患者组在所有BICAMS测试中的得分均显著较低（CVLT2：F1,110 = 28.99，p <.001；BVMTR：F1,110 = 7.77，p <.01；SDMT：F1,110 = 21.09，p <.001）。混合因素ANCOVA测试了CVLT2和BVMTR各试验学习曲线的差异。HC在CVLT2（F1,111 = 10.82，p <.01）和BVMTR（F1,110 = 7.8l6.p <.01）上的学习曲线均显著更陡。这些结果支持了巴西葡萄牙语版的诊断效度。SDMT、CVLT2和BVMTR的重测信度令人满意（分别为.86、.84和.77）。
结果表明，一旦完整的常模数据可用，这个巴西版的BICAMS将是一个有效且可靠的测量工具。
