Bachtiar Endang W, Soejoedono Retno D, Bachtiar Boy M, Henrietta Alisya, Farhana Nur, Yuniastuti Mindya
Interv Med Appl Sci. 2015 Sep;7(3):118-23. doi: 10.1556/1646.7.2015.3.6. Epub 2015 Sep 28.
This study aims to evaluate the eff ect of soybean milk containing a combination of anti-Streptococcus mutans IgY and chitosan to the colonization of S. mutans in the saliva and to the IgY persistency in the saliva.
Experimental malnourished Sprague-Dawley rats were fed with soybean milk that is enriched with anti-S. mutans IgY and chitosan. After 15 days of feeding, we evaluated the S. mutans in dental biofilm, in addition to the persistency level of anti-S. mutans IgY.
The rats that received soybean milk supplemented with anti-S. mutans IgY had the lowest number of S. mutans colonies (p < 0.05). Anti-S. mutans IgY was detected in saliva after 15 days of feeding.
Soybean milk supplemented with anti-S. mutans IgY and chitosan could signifi cantly reduce S. mutans biofilm, and the supplemented anti-S. mutans IgY persisted in these rats' saliva following the feeding period.
本研究旨在评估含有抗变形链球菌IgY和壳聚糖组合的豆浆对唾液中变形链球菌定植以及唾液中IgY持久性的影响。
用富含抗变形链球菌IgY和壳聚糖的豆浆喂养实验性营养不良的斯普拉格-道利大鼠。喂养15天后,我们评估了牙菌斑中的变形链球菌,以及抗变形链球菌IgY的持久性水平。
接受补充抗变形链球菌IgY豆浆的大鼠变形链球菌菌落数最低(p < 0.05)。喂养15天后在唾液中检测到抗变形链球菌IgY。
补充抗变形链球菌IgY和壳聚糖的豆浆可显著减少变形链球菌生物膜,并且在喂养期后,补充的抗变形链球菌IgY在这些大鼠的唾液中持续存在。