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豆浆、壳聚糖和抗变形链球菌IgY对营养不良大鼠牙菌斑的影响及IgY在唾液中的持久性。

Effects of soybean milk, chitosan, and anti-Streptococcus mutans IgY in malnourished rats' dental biofilm and the IgY persistency in saliva.

作者信息

Bachtiar Endang W, Soejoedono Retno D, Bachtiar Boy M, Henrietta Alisya, Farhana Nur, Yuniastuti Mindya

出版信息

Interv Med Appl Sci. 2015 Sep;7(3):118-23. doi: 10.1556/1646.7.2015.3.6. Epub 2015 Sep 28.

Abstract

OBJECTIVE

This study aims to evaluate the eff ect of soybean milk containing a combination of anti-Streptococcus mutans IgY and chitosan to the colonization of S. mutans in the saliva and to the IgY persistency in the saliva.

MATERIALS AND METHODS

Experimental malnourished Sprague-Dawley rats were fed with soybean milk that is enriched with anti-S. mutans IgY and chitosan. After 15 days of feeding, we evaluated the S. mutans in dental biofilm, in addition to the persistency level of anti-S. mutans IgY.

RESULTS

The rats that received soybean milk supplemented with anti-S. mutans IgY had the lowest number of S. mutans colonies (p < 0.05). Anti-S. mutans IgY was detected in saliva after 15 days of feeding.

CONCLUSIONS

Soybean milk supplemented with anti-S. mutans IgY and chitosan could signifi cantly reduce S. mutans biofilm, and the supplemented anti-S. mutans IgY persisted in these rats' saliva following the feeding period.

摘要

目的

本研究旨在评估含有抗变形链球菌IgY和壳聚糖组合的豆浆对唾液中变形链球菌定植以及唾液中IgY持久性的影响。

材料与方法

用富含抗变形链球菌IgY和壳聚糖的豆浆喂养实验性营养不良的斯普拉格-道利大鼠。喂养15天后,我们评估了牙菌斑中的变形链球菌,以及抗变形链球菌IgY的持久性水平。

结果

接受补充抗变形链球菌IgY豆浆的大鼠变形链球菌菌落数最低(p < 0.05)。喂养15天后在唾液中检测到抗变形链球菌IgY。

结论

补充抗变形链球菌IgY和壳聚糖的豆浆可显著减少变形链球菌生物膜,并且在喂养期后,补充的抗变形链球菌IgY在这些大鼠的唾液中持续存在。

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