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J Natl Cancer Inst. 2015 Jun 25;107(9). doi: 10.1093/jnci/djv179. Print 2015 Sep.
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Breast. 2015 Oct;24(5):582-7. doi: 10.1016/j.breast.2015.05.006. Epub 2015 Jun 19.
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The potential utility of acetyltanshinone IIA in the treatment of HER2-overexpressed breast cancer: Induction of cancer cell death by targeting apoptotic and metabolic signaling pathways.乙酰丹参酮IIA在治疗HER2过表达乳腺癌中的潜在效用:通过靶向凋亡和代谢信号通路诱导癌细胞死亡。
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一项为期12周的步行锻炼计划对正在接受化疗的乳腺癌患者身体成分和免疫细胞计数的影响。

Effect of a 12-week walking exercise program on body composition and immune cell count in patients with breast cancer who are undergoing chemotherapy.

作者信息

Kim Ji Jeong, Shin Yun A, Suk Min Hwa

机构信息

College of Sports Science, Department of exercise prescription and rehabilitation, Dankook University, Cheonan, Republic of Korea.

出版信息

J Exerc Nutrition Biochem. 2015 Sep;19(3):255-62. doi: 10.5717/jenb.2015.15092812. Epub 2015 Sep 30.

DOI:10.5717/jenb.2015.15092812
PMID:26525495
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4624127/
Abstract

PURPOSE

The purpose of this study was to examine the effect of a 12-week walking exercise program on body composition and immune cell count in patients with breast cancer who are undergoing chemotherapy.

METHODS

Twenty patients (age, 47.8 ± 3.12) participated in the study. Body composition (weight, body mass index, muscle weight, body fat mass, and percent body fat) and the cell counts for immune cells (white blood corpuscles, lymphocytes, helper T cells, cytotoxic T cells, natural killer cells, and natural killer T cells) were measured before and after the 12-week walking exercise program. SPSS 17.0 statistical software was used. The two-way repeated ANOVA with post hoc was used to determine the difference between time and interaction.

RESULTS

There were significant reductions in the weight (p < .05), BMI (p < .01), and percent body fat (p < .05) after the 12-week walking exercise program. However, the immune cell counts did not change significantly.

CONCLUSION

These results indicated that the 12-week walking exercise program had an effect on the balances among weight, BMI and percent body fat in patients with breast cancer.

摘要

目的

本研究旨在探讨为期12周的步行锻炼计划对正在接受化疗的乳腺癌患者身体成分和免疫细胞计数的影响。

方法

20名患者(年龄47.8±3.12)参与了本研究。在为期12周的步行锻炼计划前后,测量身体成分(体重、体重指数、肌肉重量、体脂肪量和体脂百分比)以及免疫细胞的细胞计数(白细胞、淋巴细胞、辅助性T细胞、细胞毒性T细胞、自然杀伤细胞和自然杀伤T细胞)。使用SPSS 17.0统计软件。采用带有事后检验的双向重复方差分析来确定时间和交互作用之间的差异。

结果

为期12周的步行锻炼计划后,体重(p<.05)、体重指数(p<.01)和体脂百分比(p<.05)均有显著下降。然而,免疫细胞计数没有显著变化。

结论

这些结果表明,为期12周的步行锻炼计划对乳腺癌患者的体重、体重指数和体脂百分比之间的平衡有影响。