Deák Klára, Fejes Imre, Janáky Márta, Várkonyi Tamás, Benedek György, Braunitzer Gábor
Department of Ophthalmology, Faculty of Medicine, University of Szeged, Szeged, Hungary.
Med Princ Pract. 2016;25(3):282-5. doi: 10.1159/000442163. Epub 2015 Dec 2.
To assess the utility of visual electrophysiological methods, visual evoked potentials (VEPs) and pattern electroretinograms (PERGs) were recorded for the detection of subclinical optic nerve and retinal involvement in patients with diabetes mellitus.
The data of 63 patients (126 eyes) with no vascular retinopathy or optic neuropathy were retrospectively analyzed. The patients were divided into polyneuropathic/nonpolyneuropathic groups to differentiate between early and late subclinical stages. The recorded parameters were compared with local reference values.
116 eyes (92%) had VEP and 76 (60%) had PERG abnormalities. The most frequent alteration was latency delay, but waveform and amplitude irregularities were also observed. The simultaneous use of the two methods allowed us to differentiate abnormal VEPs of purely optic nerve origin from those reflecting retinal involvement.
We suggest that regular electrophysiological screening should receive more attention in the ophthalmological care of diabetic patients.
为评估视觉电生理方法的效用，对糖尿病患者记录视觉诱发电位（VEP）和图形视网膜电图（PERG）以检测亚临床视神经和视网膜受累情况。
回顾性分析63例（126只眼）无视网膜血管病变或视神经病变患者的数据。将患者分为多发性神经病变/非多发性神经病变组，以区分亚临床早期和晚期。将记录的参数与当地参考值进行比较。
116只眼（92%）VEP异常，76只眼（60%）PERG异常。最常见的改变是潜伏期延迟，但也观察到波形和振幅不规则。同时使用这两种方法使我们能够区分单纯视神经起源的异常VEP和反映视网膜受累的异常VEP。
我们建议在糖尿病患者的眼科护理中，应更加重视定期的电生理筛查。
