一种使用聚合物包覆光纤尖端的pH值和过氧化氢双传感器。
A Dual Sensor for pH and Hydrogen Peroxide Using Polymer-Coated Optical Fibre Tips.
作者信息
Purdey Malcolm S, Thompson Jeremy G, Monro Tanya M, Abell Andrew D, Schartner Erik P
机构信息
ARC Centre of Excellence for Nanoscale BioPhotonics, Adelaide 5005, SA, Australia.
Institute for Photonics and Advanced Sensing (IPAS), The University of Adelaide, North Terrace, Adelaide 5005, SA, Australia.
出版信息
Sensors (Basel). 2015 Dec 17;15(12):31904-13. doi: 10.3390/s151229893.
Abstract
This paper demonstrates the first single optical fibre tip probe for concurrent detection of both hydrogen peroxide (H₂O₂) concentration and pH of a solution. The sensor is constructed by embedding two fluorophores: carboxyperoxyfluor-1 (CPF1) and seminaphtharhodafluor-2 (SNARF2) within a polymer matrix located on the tip of the optical fibre. The functionalised fibre probe reproducibly measures pH, and is able to accurately detect H₂O₂ over a biologically relevant concentration range. This sensor offers potential for non-invasive detection of pH and H₂O₂ in biological environments using a single optical fibre.
摘要
本文展示了首个用于同时检测过氧化氢（H₂O₂）浓度和溶液pH值的单光纤尖端探针。该传感器通过将两种荧光团：羧基过氧氟-1（CPF1）和半萘罗丹氟-2（SNARF2）嵌入位于光纤尖端的聚合物基质中构建而成。功能化光纤探针可重复测量pH值，并能够在生物学相关浓度范围内准确检测H₂O₂。这种传感器为使用单根光纤在生物环境中无创检测pH值和H₂O₂提供了可能性。
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