Kiliçkaya M Mustafa, Tuz Mustafa, Yariktaş Murat, Yasan Hasan, Aynalı Giray, Bagci Özkan
Department of Otolaryngology, Medical Faculty of Suleyman Demirel University, 32100 Isparta, Turkey.
Department of Medical Genetics, Medical Faculty of Suleyman Demirel University, 32100 Isparta, Turkey.
Int J Otolaryngol. 2015;2015:981950. doi: 10.1155/2015/981950. Epub 2015 Dec 2.
Objective. The purpose of this study was to investigate whether or not there was a correlation between the neutrophil-to-lymphocyte ratio (NLR) value and the severity of idiopathic peripheral facial palsy (IPFP) and to determine whether or not NLR could be used as an early predictive parameter in the prognosis of IPFP patients. Material and Method. This retrospective study was conducted on 146 patients who were diagnosed with IPFP. The control group comprised 140 patients. Patients with IPFP were categorized according to the House-Brackmann grading system (HBS). The NLR value was obtained by dividing the neutrophil value by the lymphocyte value. Results. In the IPFP group, the mean NLR value was 3.63 ± 2.74 and, in the control group, 1.84 ± 0.78. The mean NLR value was significantly higher in IPFP patients than in the control subjects (p < 0.0001). The mean NLR value in group A (Grades I-II ) was 2.61 ± 2.28, in group B (Grades III-IV) 3.22 ± 2.65, and in group C (Grades V-VI) 10.69 ± 6.30. Conclusion. We determined that as the severity of IPFP increased, the NLR value increased. The NLR value can be used as a prognostic factor in the early prediction of IPFP prognosis.
目的。本研究旨在探讨中性粒细胞与淋巴细胞比值（NLR）值与特发性周围性面神经麻痹（IPFP）严重程度之间是否存在相关性，并确定NLR是否可作为IPFP患者预后的早期预测参数。材料与方法。本回顾性研究对146例诊断为IPFP的患者进行。对照组包括140例患者。IPFP患者根据House-Brackmann分级系统（HBS）进行分类。NLR值通过中性粒细胞值除以淋巴细胞值获得。结果。IPFP组的平均NLR值为3.63±2.74，对照组为1.84±0.78。IPFP患者的平均NLR值显著高于对照组（p<0.0001）。A组（I-II级）的平均NLR值为2.61±2.28，B组（III-IV级）为3.22±2.65，C组（V-VI级）为10.69±6.30。结论。我们确定，随着IPFP严重程度的增加，NLR值升高。NLR值可作为IPFP预后早期预测的一个预后因素。
