在一个活猪模型中，一种具有全景可视化功能的新型结肠镜比传统结肠镜检测到更多模拟息肉。
A novel colonoscope with panoramic visualization detected more simulated polyps than conventional colonoscopy in a live swine model.
作者信息
Gluck Nathan, Fishman Sigal, Melhem Alaa, Goldfarb Sharon, Halpern Zamir, Santo Erwin
机构信息
Tel Aviv Medical Center, Tel-Aviv, Israel.- ; Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
GI View Ltd, Ramat Gan, Israel.
出版信息
Endosc Int Open. 2015 Dec;3(6):E642-5. doi: 10.1055/s-0034-1393080. Epub 2015 Oct 6.
BACKGROUND AND STUDY AIMS
The Aer-O-Scope™ Colonoscope System (AOS) combines panoramic 360° view with standard forward view. We assessed the AOS's ability to identify lesions implanted in live swine, compared to conventional colonoscopy (CC).
PATIENTS AND METHODS
Twelve swine colons were surgically ligated and beads sewn within. Five procedures (3 AOS and 2 CC) were performed on each swine and findings reported. Physicians were blinded to number, size, and color of beads. The sequence of procedures and physicians was randomized. Pigs, physicians, and colonoscopes were randomly alternated between examination rooms, maintaining physician blindness. Two independent blinded physicians interpreted procedure videos offline.
RESULTS
A total of 259 /273 (94.9 %) of lesions were visualized by AOS compared to 158 /182 with CC (86.8 %) (P = 0.002). Miss rates of lesions ≥ 6 mm were 2.6 % and 10.5 %, respectively (P = 0.022), and 6.9 % and 15.1 %, respectively, for lesions < 6 mm (P = 0.031). Mean agreement between AOS and CC for lesion detection was 88.3 %. The benefit of AOS was maintained in offline video review.
CONCLUSIONS
AOS, featuring panoramic 360° view, demonstrated high detection rates for simulated colonic lesions in a live swine model.
背景与研究目的
Aer-O-Scope™ 结肠镜系统（AOS）将360°全景视图与标准前视视图相结合。我们将AOS与传统结肠镜检查（CC）相比较，评估其识别植入活猪体内病变的能力。
患者与方法
对12头猪的结肠进行手术结扎，并在内部缝入珠子。每头猪进行5次操作（3次AOS和2次CC），并报告结果。医生对珠子的数量、大小和颜色不知情。操作顺序和医生均随机安排。猪、医生和结肠镜在检查室之间随机交替，以保持医生不知情。两名独立的不知情医生离线解读操作视频。
结果
AOS观察到259/273（94.9%）的病变，而CC观察到158/182（86.8%）（P = 0.002）。≥6mm病变的漏诊率分别为2.6%和10.5%（P = 0.022），<6mm病变的漏诊率分别为6.9%和15.1%（P = 0.031）。AOS和CC在病变检测方面的平均一致性为88.3%。离线视频回顾时，AOS的优势依然存在。
结论
具有360°全景视图的AOS在活猪模型中对模拟结肠病变显示出高检出率。
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