Hashemi Hassan, Khabazkhoob Mehdi, Emamian Mohammad Hassan, Shariati Mohammad, Miraftab Mohammad, Yekta Abbasali, Ostadimoghaddam Hadi, Fotouhi Akbar
Noor Ophthalmology Research Center, Noor Eye Hospital, Tehran, Iran.
Center for Health Related Social and Behavioral Sciences Research, Shahroud University of Medical Sciences, Shahroud, Iran.
J Ophthalmic Vis Res. 2015 Jul-Sep;10(3):214-20. doi: 10.4103/2008-322X.170340.
To investigate the association between ocular biometrics such as axial length (AL), anterior chamber depth (ACD), lens thickness (LT), vitreous chamber depth (VCD) and corneal power (CP) with different refractive errors.
In a cross-sectional study on the 40 to 64-year-old population of Shahroud, random cluster sampling was performed. Ocular biometrics were measured using the Allegro Biograph (WaveLight AG, Erlangen, Germany) for all participants. Refractive errors were determined using cycloplegic refraction.
In the first model, the strongest correlations were found between spherical equivalent with axial length and corneal power. Spherical equivalent was strongly correlated with axial length in high myopic and high hyperopic cases, and with corneal power in high hyperopic cases; 69.5% of variability in spherical equivalent was attributed to changes in these variables. In the second model, the correlations between vitreous chamber depth and corneal power with spherical equivalent were stronger in myopes than hyperopes, while the correlations between lens thickness and anterior chamber depth with spherical equivalent were stronger in hyperopic cases than myopic ones. In the third model, anterior chamber depth + lens thickness correlated with spherical equivalent only in moderate and severe cases of hyperopia, and this index was not correlated with spherical equivalent in moderate to severe myopia.
In individuals aged 40-64 years, corneal power and axial length make the greatest contribution to spherical equivalent in high hyperopia and high myopia. Anterior segment biometric components have a more important role in hyperopia than myopia.
研究眼生物特征参数如眼轴长度（AL）、前房深度（ACD）、晶状体厚度（LT）、玻璃体腔深度（VCD）和角膜屈光力（CP）与不同屈光不正之间的关联。
在一项针对设拉子40至64岁人群的横断面研究中，采用随机整群抽样。所有参与者均使用Allegro Biograph（德国爱尔朗根威视博光学公司）测量眼生物特征参数。使用散瞳验光确定屈光不正情况。
在第一个模型中，发现球镜等效度与眼轴长度和角膜屈光力之间的相关性最强。在高度近视和高度远视病例中，球镜等效度与眼轴长度密切相关，在高度远视病例中与角膜屈光力密切相关；球镜等效度69.5%的变异性归因于这些变量的变化。在第二个模型中，近视患者中玻璃体腔深度和角膜屈光力与球镜等效度的相关性比远视患者更强，而远视病例中晶状体厚度和前房深度与球镜等效度的相关性比近视患者更强。在第三个模型中，前房深度 + 晶状体厚度仅在中度和重度远视病例中与球镜等效度相关，而在中度至重度近视中该指标与球镜等效度不相关。
在40 - 64岁个体中，角膜屈光力和眼轴长度在高度远视和高度近视中对球镜等效度的贡献最大。眼前节生物特征成分在远视中比近视中发挥更重要的作用。
