• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

2014/15年在美国传播的H3N2流感病毒的演变：对疫苗效力的影响及可能引发的新疫情

Evolution of 2014/15 H3N2 Influenza Viruses Circulating in US: Consequences for Vaccine Effectiveness and Possible New Pandemic.

作者信息

Veljkovic Veljko, Paessler Slobodan, Glisic Sanja, Prljic Jelena, Perovic Vladimir R, Veljkovic Nevena, Scotch Matthew

机构信息

Center for Multidisciplinary Research, Institute of Nuclear Sciences Vinca, University of Belgrade Belgrade, Serbia.

Galveston National Laboratory, Department of Pathology, University of Texas Medical Branch Galveston, TX, USA.

出版信息

Front Microbiol. 2015 Dec 22;6:1456. doi: 10.3389/fmicb.2015.01456. eCollection 2015.

DOI:10.3389/fmicb.2015.01456
PMID:26733989
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4686605/
Abstract

A key factor in the effectiveness of the seasonal influenza vaccine is its immunological compatibility with the circulating viruses during the season. Here we propose a new bioinformatics approach for analysis of influenza viruses which could be used as an efficient tool for selection of vaccine viruses, assessment of the effectiveness of seasonal influenza vaccines, and prediction of the epidemic/pandemic potential of novel influenza viruses.

摘要

季节性流感疫苗有效性的一个关键因素是其在季节期间与流行病毒的免疫相容性。在此，我们提出一种用于分析流感病毒的新生物信息学方法，该方法可用作选择疫苗病毒、评估季节性流感疫苗有效性以及预测新型流感病毒流行/大流行潜力的有效工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6dd9/4686605/4beb91ea994f/fmicb-06-01456-g0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6dd9/4686605/d79f5fe3ffc8/fmicb-06-01456-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6dd9/4686605/f856002d8619/fmicb-06-01456-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6dd9/4686605/641d5123a484/fmicb-06-01456-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6dd9/4686605/78f140818465/fmicb-06-01456-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6dd9/4686605/d6bc931be7fd/fmicb-06-01456-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6dd9/4686605/4beb91ea994f/fmicb-06-01456-g0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6dd9/4686605/d79f5fe3ffc8/fmicb-06-01456-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6dd9/4686605/f856002d8619/fmicb-06-01456-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6dd9/4686605/641d5123a484/fmicb-06-01456-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6dd9/4686605/78f140818465/fmicb-06-01456-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6dd9/4686605/d6bc931be7fd/fmicb-06-01456-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6dd9/4686605/4beb91ea994f/fmicb-06-01456-g0006.jpg

相似文献

1
Evolution of 2014/15 H3N2 Influenza Viruses Circulating in US: Consequences for Vaccine Effectiveness and Possible New Pandemic.2014/15年在美国传播的H3N2流感病毒的演变：对疫苗效力的影响及可能引发的新疫情
Front Microbiol. 2015 Dec 22;6:1456. doi: 10.3389/fmicb.2015.01456. eCollection 2015.
2
Prediction of influenza vaccine effectiveness for the influenza season 2017/18 in the US.2017/18年美国流感季节流感疫苗有效性的预测。
F1000Res. 2017 Nov 29;6:2067. doi: 10.12688/f1000research.13198.1. eCollection 2017.
3
Genetic analysis of HA1 domain of influenza A/H3N2 viruses isolated in Kenya during the 2007-2013 seasons reveal significant divergence from WHO-recommended vaccine strains.对肯尼亚 2007-2013 年期间分离的甲型 H3N2 流感病毒 HA1 结构域的遗传分析显示，与世界卫生组织推荐的疫苗株存在显著差异。
Int J Infect Dis. 2020 Jun;95:413-420. doi: 10.1016/j.ijid.2020.04.001. Epub 2020 Apr 7.
4
Early estimates of seasonal influenza vaccine effectiveness - United States, January 2015.早期季节性流感疫苗效力估计 - 美国，2015 年 1 月。
MMWR Morb Mortal Wkly Rep. 2015 Jan 16;64(1):10-5.
5
Interim Estimates of 2021-22 Seasonal Influenza Vaccine Effectiveness - United States, February 2022.2021-22 年度季节性流感疫苗效力的临时估计-美国，2022 年 2 月。
MMWR Morb Mortal Wkly Rep. 2022 Mar 11;71(10):365-370. doi: 10.15585/mmwr.mm7110a1.
6
A virus-like particle vaccination strategy expands its tolerance to H3N2 antigenic drift by enhancing neutralizing antibodies against hemagglutinin stalk.一种病毒样颗粒疫苗接种策略通过增强针对血凝素茎部的中和抗体来扩大其对H3N2抗原漂移的耐受性。
Antiviral Res. 2017 Apr;140:62-75. doi: 10.1016/j.antiviral.2017.01.010. Epub 2017 Jan 14.
7
[Epidemiological features of prevalent influenza A viruses in children with influenza-like illness during the 2004-2017 season in Beijing].[2004 - 2017年北京地区流感样病例儿童中流行甲型流感病毒的流行病学特征]
Zhonghua Er Ke Za Zhi. 2018 Jun 2;56(6):429-434. doi: 10.3760/cma.j.issn.0578-1310.2018.06.005.
8
The genetic match between vaccine strains and circulating seasonal influenza A viruses in Vietnam, 2001-2009.2001-2009 年越南疫苗株与季节性甲型流感病毒循环株之间的基因匹配性。
Influenza Other Respir Viruses. 2013 Nov;7(6):1151-7. doi: 10.1111/irv.12038. Epub 2012 Nov 8.
9
Diversity in the Circulation of Influenza A(H3N2) Viruses in the Northern Hemisphere in the 2018-19 Season.2018 - 19年北半球甲型（H3N2）流感病毒传播的多样性
Vaccines (Basel). 2021 Apr 13;9(4):375. doi: 10.3390/vaccines9040375.
10
Differential Antibody Recognition of H3N2 Vaccine and Seasonal Influenza Virus Strains Based on Age, Vaccine Status, and Sex in the 2017-2018 Season.基于年龄、疫苗接种状态和性别的差异，2017-2018 年季节中 H3N2 疫苗和季节性流感病毒株的抗体识别。
J Infect Dis. 2020 Sep 14;222(8):1371-1382. doi: 10.1093/infdis/jiaa289.

引用本文的文献

1
Prediction of Antigenic Distance in Influenza A Using Attribute Network Embedding.使用属性网络嵌入预测甲型流感的抗原距离。
Viruses. 2023 Jun 29;15(7):1478. doi: 10.3390/v15071478.
2
Predicting Antigenic Distance from Genetic Data for PRRSV-Type 1: Applications of Machine Learning.预测 PRRSV-1 型的遗传数据的抗原距离：机器学习的应用。
Microbiol Spectr. 2023 Feb 14;11(1):e0408522. doi: 10.1128/spectrum.04085-22. Epub 2022 Dec 13.
3
Antigenicity prediction and vaccine recommendation of human influenza virus A (H3N2) using convolutional neural networks.

本文引用的文献

1
Novel Reassortant Human-Like H3N2 and H3N1 Influenza A Viruses Detected in Pigs Are Virulent and Antigenically Distinct from Swine Viruses Endemic to the United States.在猪身上检测到的新型重配人源化H3N2和H3N1甲型流感病毒具有致病性，且在抗原性上与美国流行的猪病毒不同。
J Virol. 2015 Nov;89(22):11213-22. doi: 10.1128/JVI.01675-15. Epub 2015 Aug 26.
2
In Silico Prediction and Experimental Confirmation of HA Residues Conferring Enhanced Human Receptor Specificity of H5N1 Influenza A Viruses.甲型H5N1流感病毒增强人类受体特异性的血凝素残基的计算机模拟预测与实验验证
Sci Rep. 2015 Jun 19;5:11434. doi: 10.1038/srep11434.
3
Low effectiveness of seasonal influenza vaccine in preventing laboratory-confirmed influenza in primary care in the United Kingdom: 2014/15 mid-season results.
使用卷积神经网络预测人类流感病毒 A（H3N2）的抗原性并推荐疫苗。
Hum Vaccin Immunother. 2020 Nov 1;16(11):2690-2708. doi: 10.1080/21645515.2020.1734397. Epub 2020 Aug 4.
4
Evolution of H5-Type Avian Influenza A Virus Towards Mammalian Tropism in Egypt, 2014 to 2015.2014年至2015年埃及H5型甲型禽流感病毒向嗜哺乳动物性的演变
Pathogens. 2019 Nov 7;8(4):224. doi: 10.3390/pathogens8040224.
5
Optimizing the impact of low-efficacy influenza vaccines.优化低效能流感疫苗的效果。
Proc Natl Acad Sci U S A. 2018 May 15;115(20):5151-5156. doi: 10.1073/pnas.1802479115. Epub 2018 Apr 30.
6
The Hard Way towards an Antibody-Based HIV-1 Env Vaccine: Lessons from Other Viruses.迈向基于抗体的 HIV-1 Env 疫苗的艰难之路：来自其他病毒的教训。
Viruses. 2018 Apr 15;10(4):197. doi: 10.3390/v10040197.
7
Prediction of influenza vaccine effectiveness for the influenza season 2017/18 in the US.2017/18年美国流感季节流感疫苗有效性的预测。
F1000Res. 2017 Nov 29;6:2067. doi: 10.12688/f1000research.13198.1. eCollection 2017.
8
Seasonal influenza vaccine effectiveness against laboratory-confirmed influenza in 2015-2016: a hospital-based test-negative casecontrol study in Lithuania.2015 - 2016年季节性流感疫苗对实验室确诊流感的有效性：立陶宛一项基于医院的检测阴性病例对照研究
BMJ Open. 2017 Oct 10;7(10):e017835. doi: 10.1136/bmjopen-2017-017835.
9
Predicted Enhanced Human Propensity of Current Avian-Like H1N1 Swine Influenza Virus from China.对源自中国的当前类禽H1N1猪流感病毒增强的人类易感性预测
PLoS One. 2016 Nov 9;11(11):e0165451. doi: 10.1371/journal.pone.0165451. eCollection 2016.
英国基层医疗中季节性流感疫苗预防实验室确诊流感的效果不佳：2014/15年季中结果
Euro Surveill. 2015 Feb 5;20(5):21025.
4
Novel phylogenetic algorithm to monitor human tropism in Egyptian H5N1-HPAIV reveals evolution toward efficient human-to-human transmission.新型进化算法监测埃及 H5N1-HPAIV 对人类的嗜性，揭示其向高效人际传播进化的趋势。
PLoS One. 2013 Apr 26;8(4):e61572. doi: 10.1371/journal.pone.0061572. Print 2013.
5
Conserved synthetic peptides from the hemagglutinin of influenza viruses induce broad humoral and T-cell responses in a pig model.流感病毒血凝素的保守合成肽在猪模型中诱导广泛的体液和 T 细胞反应。
PLoS One. 2012;7(7):e40524. doi: 10.1371/journal.pone.0040524. Epub 2012 Jul 16.
6
Evolution of novel reassortant A/H3N2 influenza viruses in North American swine and humans, 2009-2011.2009-2011 年，新型重配 A/H3N2 流感病毒在北美猪群和人群中的演变。
J Virol. 2012 Aug;86(16):8872-8. doi: 10.1128/JVI.00259-12. Epub 2012 Jun 13.
7
MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods.MEGA5：用于最大似然法、进化距离法和最大简约法的分子进化遗传学分析。
Mol Biol Evol. 2011 Oct;28(10):2731-9. doi: 10.1093/molbev/msr121. Epub 2011 May 4.
8
Identification of hemagglutinin structural domain and polymorphisms which may modulate swine H1N1 interactions with human receptor.鉴定血凝素结构域和可能调节猪H1N1与人受体相互作用的多态性。
BMC Struct Biol. 2009 Sep 28;9:62. doi: 10.1186/1472-6807-9-62.
9
Characterization of conserved properties of hemagglutinin of H5N1 and human influenza viruses: possible consequences for therapy and infection control.H5N1型禽流感病毒与人流感病毒血凝素保守特性的表征：对治疗和感染控制的可能影响
BMC Struct Biol. 2009 Apr 7;9:21. doi: 10.1186/1472-6807-9-21.
10
Comparison of the mutation rates of human influenza A and B viruses.甲型和乙型人流感病毒突变率的比较。
J Virol. 2006 Apr;80(7):3675-8. doi: 10.1128/JVI.80.7.3675-3678.2006.