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神经精神疾病问卷-临床医生土耳其语版的信度和效度。

The reliability and validity of the Turkish version of the Neuropsychiatric Inventory-Clinician.

出版信息

Turk J Med Sci. 2015;45(5):1087-93. doi: 10.3906/sag-1405-111.

DOI:10.3906/sag-1405-111
PMID:26738352
Abstract

BACKGROUND/AIM: The Neuropsychiatric Inventory-Clinician (NPI-C) scale is one of the best-known scales for evaluating the behavioral and psychological symptoms of dementia. This study aimed to assess the reliability and validity of the Turkish version of the NPI-C scale in patients with Alzheimer disease (AD).

MATERIALS AND METHODS

The NPI-C scale was administered to 125 patients with AD. For reliability, both Cronbach's α and interrater reliability were analyzed. The Behavioral Pathology in Alzheimer's Disease (BEHAVE-AD) scale was applied for validity and, in addition, the Mini Mental State Examination (MMSE), Instrumental Activities of Daily Living (IADL) scale, and Disability Assessment of Dementia (DAD) scale were completed.

RESULTS

The Turkish version of the NPI-C scale showed high internal consistency (Cronbach's α = 0.75) and mostly good interrater reliability. Assessments of validity showed that the NPI-C and corresponding BEHAVE-AD domains were found to be significantly correlated, between 0.925 and 0.195. Moreover, the correlations between NPI-C and MMSE were significant for all domains except the dysphoria, anxiety, and elation/euphoria domains. When we conducted a correlation analysis of NPI-C with IADL, all domains were statistically significantly correlated except aggression, anxiety, elation/euphoria, and dysphoria.

CONCLUSION

The Turkish version of the NPI-C scale was found to be a reliable and valid instrument to assess neuropsychiatric symptoms in Turkish elderly subjects with AD.

摘要

背景/目的：神经精神问卷-临床医生版（NPI-C）量表是评估痴呆患者行为和心理症状的最著名量表之一。本研究旨在评估土耳其版 NPI-C 量表在阿尔茨海默病（AD）患者中的信度和效度。

材料和方法

对 125 名 AD 患者进行了 NPI-C 量表评估。为了评估信度，分析了 Cronbach's α 和评分者间信度。采用行为病理阿尔茨海默病量表（BEHAVE-AD）进行效度评估，此外还完成了简易精神状态检查（MMSE）、日常生活活动工具（IADL）量表和痴呆残疾评估（DAD）量表。

结果

土耳其版 NPI-C 量表显示出较高的内部一致性（Cronbach's α=0.75）和较好的评分者间信度。效度评估表明，NPI-C 与相应的 BEHAVE-AD 域之间存在显著相关性，范围为 0.925 至 0.195。此外，NPI-C 与 MMSE 之间的相关性在除了抑郁、焦虑和欣快/兴奋域之外的所有域中均具有统计学意义。当我们对 NPI-C 与 IADL 进行相关分析时，除了攻击、焦虑、欣快/兴奋和抑郁外，所有域均具有统计学相关性。

结论

土耳其版 NPI-C 量表被发现是一种可靠且有效的工具，可用于评估土耳其老年 AD 患者的神经精神症状。

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