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J Clin Diagn Res. 2015 Sep;9(9):DM01-3. doi: 10.7860/JCDR/2015/14246.6530. Epub 2015 Sep 1.

2

Epidemiology of Carbapenem-Resistant Enterobacteriaceae in 7 US Communities, 2012-2013.2012 - 2013年美国7个社区耐碳青霉烯类肠杆菌科细菌的流行病学

JAMA. 2015 Oct 13;314(14):1479-87. doi: 10.1001/jama.2015.12480.

3

Detection of carbapenemase activity in Enterobacteriaceae: comparison of the carbapenem inactivation method versus the Carba NP test.肠杆菌科细菌中碳青霉烯酶活性的检测：碳青霉烯灭活法与Carba NP试验的比较

J Antimicrob Chemother. 2016 Jan;71(1):274-6. doi: 10.1093/jac/dkv283. Epub 2015 Sep 15.

4

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Emerg Infect Dis. 2015 Sep;21(9):1611-6. doi: 10.3201/eid2109.150198.

5

Evaluation of the RAPIDEC® CARBA NP, the Rapid CARB Screen® and the Carba NP test for biochemical detection of carbapenemase-producing Enterobacteriaceae.评估用于生化检测产碳青霉烯酶肠杆菌科细菌的RAPIDEC® CARBA NP、Rapid CARB Screen®和Carba NP检测方法。

J Antimicrob Chemother. 2015 Nov;70(11):3014-22. doi: 10.1093/jac/dkv213. Epub 2015 Aug 9.

6

Vital Signs: Estimated Effects of a Coordinated Approach for Action to Reduce Antibiotic-Resistant Infections in Health Care Facilities - United States.生命体征：美国医疗机构中采取协调行动减少抗生素耐药性感染的估计效果

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First Report of Ceftazidime-Avibactam Resistance in a KPC-3-Expressing Klebsiella pneumoniae Isolate.产KPC-3型肺炎克雷伯菌分离株中头孢他啶-阿维巴坦耐药性的首次报告

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Rapidec Carba NP Test for Rapid Detection of Carbapenemase Producers.用于快速检测碳青霉烯酶产生菌的Rapidec Carba NP检测法

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Evaluation of the Blue-Carba test for rapid detection of carbapenemases in gram-negative bacilli.评估Blue-Carba试验用于快速检测革兰氏阴性杆菌中的碳青霉烯酶。

J Clin Microbiol. 2015 Jun;53(6):1996-8. doi: 10.1128/JCM.03026-14. Epub 2015 Mar 25.

10

The carbapenem inactivation method (CIM), a simple and low-cost alternative for the Carba NP test to assess phenotypic carbapenemase activity in gram-negative rods.碳青霉烯灭活方法（CIM），是一种简单且低成本的替代方法，可用于替代Carba NP试验来评估革兰氏阴性杆菌中的表型碳青霉烯酶活性。

PLoS One. 2015 Mar 23;10(3):e0123690. doi: 10.1371/journal.pone.0123690. eCollection 2015.

产碳青霉烯酶的耐碳青霉烯肠杆菌科细菌检测问题

The Problem of Carbapenemase-Producing-Carbapenem-Resistant-Enterobacteriaceae Detection.

作者信息

Lutgring Joseph D, Limbago Brandi M

机构信息

Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.

Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA

出版信息

J Clin Microbiol. 2016 Mar;54(3):529-34. doi: 10.1128/JCM.02771-15. Epub 2016 Jan 6.

DOI:10.1128/JCM.02771-15

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4767976/

Abstract

The emergence and spread of carbapenemase-producing carbapenem-resistant Enterobacteriaceae (CP-CRE) are a significant clinical and public health concern. Reliable detection of CP-CRE is the first step in combating this problem. There are both phenotypic and molecular methods available for CP-CRE detection. There is no single detection method that is ideal for all situations.

摘要

产碳青霉烯酶的耐碳青霉烯肠杆菌科细菌（CP-CRE）的出现和传播是一个重大的临床和公共卫生问题。可靠检测CP-CRE是应对这一问题的第一步。有多种表型和分子方法可用于CP-CRE检测。没有一种单一的检测方法适用于所有情况。