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本文引用的文献

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Neurobehavioral Disorder Associated with Prenatal Alcohol Exposure (ND-PAE): Proposed DSM-5 Diagnosis.与产前酒精暴露相关的神经行为障碍(ND-PAE):《精神疾病诊断与统计手册》第5版(DSM-5)提议的诊断标准
Child Psychiatry Hum Dev. 2016 Apr;47(2):335-46. doi: 10.1007/s10578-015-0566-7.
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Society: Don't blame the mothers.社会:不要责怪母亲们。
Nature. 2014 Aug 14;512(7513):131-2. doi: 10.1038/512131a.
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Gene-ethanol interactions underlying fetal alcohol spectrum disorders.基因-乙醇相互作用与胎儿酒精谱系障碍。
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Prenatal alcohol exposure and offspring cognition and school performance. A 'Mendelian randomization' natural experiment.产前酒精暴露与后代认知及学业表现。一项“孟德尔随机化”自然实验。
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The association of mild, moderate, and binge prenatal alcohol exposure and child neuropsychological outcomes: a meta-analysis.轻度、中度和 binge 型产前酒精暴露与儿童神经心理学结局的关联:一项荟萃分析。
Alcohol Clin Exp Res. 2014 Jan;38(1):214-26. doi: 10.1111/acer.12214. Epub 2013 Aug 1.
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Maternal risk factors for fetal alcohol spectrum disorders: not as simple as it might seem.胎儿酒精谱系障碍的母亲风险因素:并非看上去那么简单。
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Mitogen-activated protein kinase modulates ethanol inhibition of cell adhesion mediated by the L1 neural cell adhesion molecule.丝裂原活化蛋白激酶调节 L1 神经细胞粘附分子介导的细胞黏附的乙醇抑制作用。
Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5683-8. doi: 10.1073/pnas.1221386110. Epub 2013 Feb 19.
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The effect of different alcohol drinking patterns in early to mid pregnancy on the child's intelligence, attention, and executive function.孕早期和孕中期不同饮酒模式对儿童智力、注意力和执行功能的影响。
BJOG. 2012 Sep;119(10):1180-90. doi: 10.1111/j.1471-0528.2012.03393.x. Epub 2012 Jun 20.
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Does moderate drinking harm the fetal brain? Insights from animal models.适量饮酒会损害胎儿大脑吗?来自动物模型的研究结果。
Trends Neurosci. 2012 May;35(5):284-92. doi: 10.1016/j.tins.2012.01.006. Epub 2012 Mar 6.
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Fetal alcohol spectrum disorders: an overview.胎儿酒精谱系障碍:概述。
Neuropsychol Rev. 2011 Jun;21(2):73-80. doi: 10.1007/s11065-011-9166-x. Epub 2011 Apr 16.

孕期饮酒与大脑发育:任何饮酒量都安全吗?

Drinking During Pregnancy and the Developing Brain: Is Any Amount Safe?

作者信息

Charness Michael E, Riley Edward P, Sowell Elizabeth R

机构信息

VA Boston Healthcare System and Department of Neurology, Harvard Medical School, Department of Neurology, Boston University School of Medicine, 1400 VFW Parkway, West Roxbury, MA 02132, USA.

Center for Behavioral Teratology, San Diego State University, 6330 Alvarado Court, San Diego, CA 92120, USA.

出版信息

Trends Cogn Sci. 2016 Feb;20(2):80-82. doi: 10.1016/j.tics.2015.09.011.

DOI:10.1016/j.tics.2015.09.011
PMID:26801950
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4788102/
Abstract

Heavy prenatal alcohol exposure can have lifelong, disabling effects on brain and cognition. Unlike animal studies, research on light-to-moderate drinking in humans demonstrates less consistent impact. Discussions of negative research findings in popular media underestimate potential adverse outcomes and complicate decisions about risks versus benefits of light-to-moderate drinking during pregnancy.

摘要

孕期大量饮酒会对大脑和认知产生终身性的致残影响。与动物研究不同,关于人类轻度至中度饮酒的研究显示出的影响不太一致。大众媒体对负面研究结果的讨论低估了潜在的不良后果,也使关于孕期轻度至中度饮酒的风险与益处的决策变得复杂。