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大疱性硬化性苔藓与硬斑病的关联

Association of Bullous Lichen Sclerosus and Morphea.

作者信息

Azimi Seyyede Zeinab, Aslani Fatemeh Sari, Parvizi Mohammad Mahdi, Namazi Mohammad Reza

机构信息

Center for Research & Training in Skin Diseases & Leprosy Tehran University of Medical Sciences Tehran Iran.

Molcular Dermatology Research Center, Department of Pathology School of Medicine, Shiraz University of Medical Sciences Shiraz Iran.

出版信息

Clin Case Rep. 2025 Mar 17;13(3):e70315. doi: 10.1002/ccr3.70315. eCollection 2025 Mar.

DOI:10.1002/ccr3.70315
PMID:40104082
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11913618/
Abstract

Lichen sclerosus (LSc) is an inflammatory skin disease of unknown etiology. The coexistence of LSc and morphea in the same lesion is uncommon but exists. Also, there exist a few rare cases of bullous LSc-generalized morphea overlap syndrome.

摘要

硬化性苔藓（LSc）是一种病因不明的炎症性皮肤病。LSc与硬斑病在同一皮损中并存的情况并不常见，但确实存在。此外，还有少数大疱性LSc-泛发性硬斑病重叠综合征的罕见病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36d3/11913618/3f0e23304841/CCR3-13-e70315-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36d3/11913618/1377e0ef8623/CCR3-13-e70315-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36d3/11913618/e3e9e07d600b/CCR3-13-e70315-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36d3/11913618/3f0e23304841/CCR3-13-e70315-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36d3/11913618/1377e0ef8623/CCR3-13-e70315-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36d3/11913618/e3e9e07d600b/CCR3-13-e70315-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36d3/11913618/3f0e23304841/CCR3-13-e70315-g001.jpg

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1
Association of Bullous Lichen Sclerosus and Morphea.大疱性硬化性苔藓与硬斑病的关联
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2
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本文引用的文献

1
Coexistence of Lichen Sclerosus Et Atrophicus and Morphea in the Same Lesion: A Case Report.同一皮损中硬化萎缩性苔藓与硬斑病并存：一例报告
Cureus. 2023 Aug 7;15(8):e43062. doi: 10.7759/cureus.43062. eCollection 2023 Aug.
2
Bullous lichen sclerosus-generalized morphea overlap syndrome improved by tofacitinib.类天疱疮样硬皮病-泛发性硬斑病重叠综合征经托法替尼治疗改善。
Dermatol Ther. 2022 Dec;35(12):e15942. doi: 10.1111/dth.15942. Epub 2022 Nov 3.
3
Histopathological Coexistence of Extragenital Lichen Sclerosus and Morphea in a Single Lesion.
单个病灶中生殖器外硬化性苔藓和硬斑病的组织病理学共存
Cureus. 2020 Dec 22;12(12):e12215. doi: 10.7759/cureus.12215.
4
Morphea: a practical review of its diagnosis, classification and treatment.硬斑病：关于其诊断、分类及治疗的实用综述
Gac Med Mex. 2019;155(5):483-491. doi: 10.24875/GMM.M20000336.
5
[Morphea or localized scleroderma and extragenital lichen sclerosus].[硬斑病或局限性硬皮病与外生殖器外硬化性苔藓]
Hautarzt. 2018 Nov;69(11):892-900. doi: 10.1007/s00105-018-4266-7.
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German guidelines for the diagnosis and therapy of localized scleroderma.德国局限性硬皮病诊断与治疗指南。
J Dtsch Dermatol Ges. 2016 Feb;14(2):199-216. doi: 10.1111/ddg.12724.
7
Extragenital bullous lichen sclerosus.外阴部大疱性硬化性苔藓。
J Am Acad Dermatol. 2014 Nov;71(5):981-4. doi: 10.1016/j.jaad.2014.06.037. Epub 2014 Jul 31.
8
Coexistence of lichen sclerosus and morphea: a retrospective analysis of 472 patients with localized scleroderma from a German tertiary referral center.局限性硬皮病中硬化性苔藓和硬斑病共存：德国三级转诊中心 472 例局限性硬皮病患者的回顾性分析。
J Am Acad Dermatol. 2012 Dec;67(6):1157-62. doi: 10.1016/j.jaad.2012.04.003. Epub 2012 Apr 24.
9
A case of lichen sclerosus et atrophicus accompanying bullous morphea.1例硬化萎缩性苔藓伴大疱性硬斑病。
Ann Dermatol. 2011 Dec;23(Suppl 3):S354-9. doi: 10.5021/ad.2011.23.S3.S354. Epub 2011 Dec 27.
10
Coexistence of lichen sclerosus with morphoea showing bilateral symmetry.硬化性苔藓与硬斑病并存，呈双侧对称。
Clin Exp Dermatol. 2009 Oct;34(7):e416-8. doi: 10.1111/j.1365-2230.2009.03396.x.