Cohen P R, Grossman M E
Clin Exp Dermatol. 1989 Jul;14(4):273-6. doi: 10.1111/j.1365-2230.1989.tb01978.x.
Some similarities and several differences in the epidemiological, morphological, therapeutic, and prognostic features of HIV-associated disseminated HZV infection and disseminated HZV infection occurring in HIV-seronegative immunosuppressed patients exist. The severity of the cutaneous disseminated HZV infection, the potential for significant HZV-related morbidity, and the poor prognosis associated with this infection in HIV-seropositive patients, warrants prompt therapeutic intervention. The emergence of acyclovir-resistant HZV infection emphasizes the importance of continued investigation of alternative therapies for individuals with coincident HIV infection.
HIV 相关播散性 HZV 感染与 HIV 血清学阴性免疫抑制患者中发生的播散性 HZV 感染在流行病学、形态学、治疗及预后特征方面存在一些相似之处和若干差异。皮肤播散性 HZV 感染的严重程度、与 HZV 相关的显著发病可能性以及 HIV 血清学阳性患者中该感染相关的不良预后，均表明需要及时进行治疗干预。阿昔洛韦耐药性 HZV 感染的出现凸显了持续研究针对合并 HIV 感染个体的替代疗法的重要性。
