人类免疫缺陷病毒感染患者的播散性带状疱疹
Disseminated herpes zoster in patients with human immunodeficiency virus infection.
作者信息
Cohen P R, Beltrani V P, Grossman M E
机构信息
Department of Dermatology, College of Physicians and Surgeons of Columbia University, New York, New York 10032.
出版信息
Am J Med. 1988 Jun;84(6):1076-80. doi: 10.1016/0002-9343(88)90315-4.
Herpes zoster virus infections occur in persons with decreased cellular immunity. A 45-year-old man is described who presented with disseminated herpes zoster as the initial manifestation of his human immunodeficiency virus infection. Disseminated herpes zoster virus infections have been reported in human immunodeficiency virus-seropositive patients. Similar to disseminated herpes zoster virus infections that occur in immunosuppressed patients seronegative for human immunodeficiency virus, an increased morbidity and responsiveness to acyclovir is observed. In contrast, the morphology of the skin lesions and the clinical course have been more severe, and the mortality has been increased. Visceral involvement has not been described.
带状疱疹病毒感染发生在细胞免疫功能下降的人群中。本文描述了一名45岁男性，其以播散性带状疱疹作为人类免疫缺陷病毒感染的初始表现。在人类免疫缺陷病毒血清学阳性患者中曾有播散性带状疱疹病毒感染的报道。与在人类免疫缺陷病毒血清学阴性的免疫抑制患者中发生的播散性带状疱疹病毒感染相似，观察到发病率增加且对阿昔洛韦反应良好。相比之下，皮肤损害的形态和临床病程更为严重，死亡率也有所增加。尚未见有内脏受累的描述。
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