用于眼部药物递送和组织工程的水凝胶

Fathi Marzieh, Barar Jaleh, Aghanejad Ayuob, Omidi Yadollah

Research Center for Pharmaceutical Nanotechnology, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.

Bioimpacts. 2015;5(4):159-64. doi: 10.15171/bi.2015.31. Epub 2015 Dec 28.

Hydrogels, as crosslinked polymeric three dimensional networks, possess unique structure and behavior in response to the internal and/or external stimuli. As a result, they offer great prospective applications in drug delivery, cell therapy and human tissue engineering. Here, we highlight the potential of hydrogels in prolonged intraocular drug delivery and ocular surface therapy using stem cells incorporated hydrogels.

水凝胶作为交联的聚合物三维网络，在响应内部和/或外部刺激时具有独特的结构和行为。因此，它们在药物递送、细胞治疗和人体组织工程方面具有广阔的应用前景。在此，我们重点介绍了水凝胶在使用掺入干细胞的水凝胶进行延长眼内药物递送和眼表治疗方面的潜力。