DeVallance E, Fournier S, Lemaster K, Moore C, Asano S, Bonner D, Donley D, Olfert I M, Chantler P D
Division of Exercise Physiology, School of Medicine, West Virginia University, P.O. Box 9227, Morgantown, WV, 26506, USA.
Center for Cardiovascular and Respiratory Sciences, School of Medicine, West Virginia University, P.O. Box 9227, Morgantown, WV, 26506, USA.
Eur J Appl Physiol. 2016 May;116(5):899-910. doi: 10.1007/s00421-016-3348-4. Epub 2016 Mar 3.
Arterial stiffness is a strong independent risk factor for cardiovascular disease and is elevated in individuals with metabolic syndrome (MetS). Resistance training is a popular form of exercise that has beneficial effects on muscle mass, strength, balance and glucose control. However, it is unknown whether resistance exercise training (RT) can lower arterial stiffness in patients with MetS. Thus, the aim of this study was to examine whether a progressive RT program would improve arterial stiffness in MetS.
A total of 57 subjects (28 healthy sedentary subjects; 29 MetS) were evaluated for arterial structure and function, including pulse wave velocity (cfPWV: arterial stiffness), before and after an 8-week period of RT or continuation of sedentary lifestyle.
We found that 8 weeks of progressive RT increased skeletal muscle strength in both Con and MetS, but did not change arterial stiffness in either MetS (cfPWV; Pre 7.9 ± 0.4 m/s vs. Post 7.7 ± 0.4 m/s) or healthy controls (cfPWV; Pre 6.9 ± 0.3 m/s vs. Post 7.0 ± 0.3 m/s). However, when cfPWV is considered as a continuous variable, high baseline measures of cfPWV tended to show a decrease in cfPWV following RT.
Eight weeks of progressive RT did not decrease the group mean values of arterial stiffness in individuals with MetS or healthy controls.
动脉僵硬度是心血管疾病的一个强大独立危险因素，在代谢综合征（MetS）患者中升高。阻力训练是一种流行的运动形式，对肌肉质量、力量、平衡和血糖控制有有益影响。然而，尚不清楚阻力运动训练（RT）是否能降低MetS患者的动脉僵硬度。因此，本研究的目的是检验渐进性RT计划是否能改善MetS患者的动脉僵硬度。
共有57名受试者（28名健康久坐受试者；29名MetS患者）在进行8周的RT或继续久坐生活方式之前和之后，接受了动脉结构和功能评估，包括脉搏波速度（cfPWV：动脉僵硬度）。
我们发现，8周的渐进性RT增加了对照组和MetS患者的骨骼肌力量，但在MetS患者（cfPWV；训练前7.9±0.4米/秒，训练后7.7±0.4米/秒）或健康对照组（cfPWV；训练前6.9±0.3米/秒，训练后7.0±0.3米/秒）中均未改变动脉僵硬度。然而，当将cfPWV视为连续变量时，cfPWV的高基线测量值在RT后倾向于显示cfPWV降低。
8周的渐进性RT并未降低MetS患者或健康对照组的动脉僵硬度组均值。
