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来自海南软珊瑚环纹肉芝软珊瑚的新型高氧化西松烷类化合物

Further New Highly Oxidative Cembranoids from the Hainan Soft Coral Sarcophyton trocheliophorum.

作者信息

Chen Wen-Ting, Liang Lin-Fu, Li Xu-Wen, Xiao Wei, Guo Yue-Wei

机构信息

State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Zhang Jiang High-Tech Park, Shanghai, 201203, People's Republic of China.

College of Material Science and Engineering, Central South University of Forestry and Technology, 498 South Shaoshan Road, Changsha, 410004, People's Republic of China.

出版信息

Nat Prod Bioprospect. 2016 Apr;6(2):97-102. doi: 10.1007/s13659-016-0088-4. Epub 2016 Mar 15.

DOI:10.1007/s13659-016-0088-4
PMID:26979061
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4805653/
Abstract

Three new highly oxidative cembranoids, sarcophytrols D-F (1-3), were obtained from the South China Sea soft coral Sarcophyton trocheliophorum, along with two known related ones (4 and 5). Their structures were elucidated by extensive spectroscopic analyses and by comparison with literature data. The discovery of these new secondary metabolites enriched the family of cembranoids deduced from the title animal.

摘要

从中国南海软珊瑚瘤状肉芝软珊瑚（Sarcophyton trocheliophorum）中获得了三种新的高氧化二萜类化合物——肉芝醇D - F（1 - 3），以及两种已知的相关化合物（4和5）。通过广泛的光谱分析并与文献数据比较，阐明了它们的结构。这些新的次生代谢产物的发现丰富了源自该动物的二萜类化合物家族。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f567/4805653/8b02968d5b89/13659_2016_88_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f567/4805653/6ab4685aaf07/13659_2016_88_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f567/4805653/8727469ceb78/13659_2016_88_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f567/4805653/af05fdf4c1a1/13659_2016_88_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f567/4805653/8b02968d5b89/13659_2016_88_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f567/4805653/6ab4685aaf07/13659_2016_88_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f567/4805653/8727469ceb78/13659_2016_88_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f567/4805653/af05fdf4c1a1/13659_2016_88_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f567/4805653/8b02968d5b89/13659_2016_88_Fig4_HTML.jpg

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本文引用的文献

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2
Prostaglandin Derivatives: Nonaromatic Phosphodiesterase-4 Inhibitors from the Soft Coral Sarcophyton ehrenbergi.前列腺素衍生物：来自软珊瑚 Sarcophyton ehrenbergi 的非芳香型磷酸二酯酶-4 抑制剂。
J Nat Prod. 2014 Aug 22;77(8):1928-36. doi: 10.1021/np500394d.
3
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Chemical Diversity in Species Belonging to Soft Coral Genus and Its Impact on Biological Activity: A Review.化学多样性在软珊瑚属物种及其对生物活性的影响：综述。
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