Lopes Patrícia da Silva, Ramos Eliezer Lucas Pires, Gómez-Hernández César, Ferreira Gabriela Lícia Santos, Rezende-Oliveira Karine
Faculdade de Ciências Integradas do Pontal, Universidade Federal de Uberlândia, Ituiutaba, MG, Brasil.
Universidade Federal do Triângulo Mineiro, Uberaba, MG, Brasil.
Rev Inst Med Trop Sao Paulo. 2015 Dec;57(6):461-5. doi: 10.1590/S0036-46652015000600001.
Despite public health campaigns and epidemiological surveillance activities, Chagas disease remains a major health problem in Latin America. According to data from the World Health Organization, there are approximately 7-8 million people infected with Trypanosoma cruzi worldwide, a large percentage of which in Latin America. This study aims to examine the serological profile of blood donors in blood banks of Hemominas hematology center, in the town of Ituiutaba, Minas Gerais State, Brazil. The study sample consisted of 53,941 blood donors, which were grouped according to gender and age. Sample collections were performed from January 1991 to December 2011, and 277 donors (0.5%) were considered serologically ineligible due to Chagas disease. Analysis of data showed no significant difference between genders. As for age, the highest proportion of ineligible donors was from 40 to 49 years (30%), and there was a positive correlation between increasing age and the percentage of patients seropositive for Chagas disease. Therefore, adopting strategies that allow the safe identification of donors with positive serology for Chagas disease is essential to reduce or eliminate indeterminate serological results.
尽管开展了公共卫生运动和流行病学监测活动，但恰加斯病仍是拉丁美洲的一个主要健康问题。根据世界卫生组织的数据，全球约有700 - 800万人感染克氏锥虫，其中很大一部分在拉丁美洲。本研究旨在调查巴西米纳斯吉拉斯州伊图伊塔巴镇Hemominas血液学中心血库中献血者的血清学特征。研究样本包括53941名献血者，按性别和年龄分组。样本采集时间为1991年1月至2011年12月，277名献血者（0.5%）因恰加斯病血清学检测不合格。数据分析显示性别之间无显著差异。在年龄方面，不合格献血者比例最高的是40至49岁（30%），且年龄增长与恰加斯病血清学阳性患者百分比之间存在正相关。因此，采取能够安全识别恰加斯病血清学阳性献血者的策略对于减少或消除不确定的血清学结果至关重要。
