Brugnone F, Perbellini L, Faccini G B, Pasini F, Maranelli G, Romeo L, Gobbi M, Zedde A
Istituto di Medicina del Lavoro dell'Università di Verona, Policlinico Borgo Roma, Italy.
Int Arch Occup Environ Health. 1989;61(5):303-11. doi: 10.1007/BF00409385.
Benzene, toluene, cumene and styrene were measured in the breath and blood of two groups of individuals. The first group included individuals belonging to a hospital staff, the second group included chemical workers who were not exposed to the abovementioned chemicals. The chemical workers were examined in plant infirmaries on the morning before the start of the workshift, and the hospital staff in the hospital infirmaries. One environmental air sample was taken in the infirmaries for each individual at the moment of the biological samplings. The environmental concentrations of benzene and styrene were significantly higher in the infirmaries of the chemical plant than in the infirmaries of the hospital. On the other hand, the environmental concentrations of toluene and cumene were not significantly different in the plant infirmaries and in the hospital infirmaries. In the hospital staff the alveolar concentrations of benzene, toluene and styrene were significantly lower than those in the chemical workers. In the hospital staff the blood concentrations of benzene, toluene and styrene were not significantly different from those in the chemical workers. Only the blood cumene concentration was significantly higher in the chemical workers. In hospital staff, smokers showed alveolar and blood concentrations of benzene and toluene that were significantly higher than those measured in the non smoker hospital staff. With reference to chemical workers, only alveolar benzene concentration was significantly higher in smokers than in non smokers.(ABSTRACT TRUNCATED AT 250 WORDS)
对两组人员的呼出气体和血液中的苯、甲苯、异丙苯和苯乙烯进行了测量。第一组包括医院工作人员,第二组包括未接触上述化学品的化工工人。化工工人在轮班前的早晨在工厂医务室接受检查,医院工作人员在医院医务室接受检查。在进行生物采样时,为每个个体在医务室采集了一个环境空气样本。化工厂医务室中苯和苯乙烯的环境浓度显著高于医院医务室。另一方面,工厂医务室和医院医务室中甲苯和异丙苯的环境浓度没有显著差异。医院工作人员中苯、甲苯和苯乙烯的肺泡浓度显著低于化工工人。医院工作人员中苯、甲苯和苯乙烯的血液浓度与化工工人没有显著差异。只有化工工人的血液异丙苯浓度显著更高。在医院工作人员中,吸烟者的苯和甲苯的肺泡和血液浓度显著高于不吸烟的医院工作人员。对于化工工人,吸烟者的肺泡苯浓度仅显著高于不吸烟者。(摘要截选至250字)