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用于单光子发射计算机断层扫描(SPECT)的新型激光处理碘化铯铊(CsI:Tl)探测器。

Novel laser-processed CsI:Tl detector for SPECT.

作者信息

Sabet H, Bläckberg L, Uzun-Ozsahin D, El-Fakhri G

机构信息

Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02129.

Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02129 and Department of Physics and Astronomy, Uppsala University, Uppsala 75120, Sweden.

出版信息

Med Phys. 2016 May;43(5):2630. doi: 10.1118/1.4947294.

Abstract

PURPOSE

The aim of this work is to demonstrate the feasibility of a novel technique for fabrication of high spatial resolution CsI:Tl scintillation detectors for single photon emission computed tomography systems.

METHODS

The scintillators are fabricated using laser-induced optical barriers technique to create optical microstructures (or optical barriers) inside the CsI:Tl crystal bulk. The laser-processed CsI:Tl crystals are 3, 5, and 10 mm in thickness. In this work, the authors focus on the simplest pattern of optical barriers in that the barriers are created in the crystal bulk to form pixel-like patterns resembling mechanically pixelated scintillators. The monolithic CsI:Tl scintillator samples are fabricated with optical barrier patterns with 1.0 × 1.0 mm(2) and 0.625 × 0.625 mm(2) pixels. Experiments were conducted to characterize the fabricated arrays in terms of pixel separation and energy resolution. A 4 × 4 array of multipixel photon counter was used to collect the scintillation light in all the experiments.

RESULTS

The process yield for fabricating the CsI:Tl arrays is 100% with processing time under 50 min. From the flood maps of the fabricated detectors exposed to 122 keV gammas, peak-to-valley (P/V) ratios of greater than 2.3 are calculated. The P/V values suggest that regardless of the crystal thickness, the pixels can be resolved.

CONCLUSIONS

The results suggest that optical barriers can be considered as a robust alternative to mechanically pixelated arrays and can provide high spatial resolution while maintaining the sensitivity in a high-throughput and cost-effective manner.

摘要

目的

本研究旨在证明一种用于制造单光子发射计算机断层扫描系统高空间分辨率碘化铯铊(CsI:Tl)闪烁探测器的新技术的可行性。

方法

采用激光诱导光学势垒技术在CsI:Tl晶体内部制造光学微结构(或光学势垒)来制作闪烁体。激光处理后的CsI:Tl晶体厚度分别为3毫米、5毫米和10毫米。在本研究中,作者专注于最简单的光学势垒图案,即在晶体内部制造势垒以形成类似机械像素化闪烁体的像素状图案。制作了像素尺寸为1.0×1.0毫米²和0.625×0.625毫米²的具有光学势垒图案的整体式CsI:Tl闪烁体样品。进行实验以根据像素间距和能量分辨率对制作的阵列进行表征。在所有实验中均使用4×4阵列的多像素光子计数器来收集闪烁光。

结果

制造CsI:Tl阵列的工艺成品率为100%,处理时间在50分钟以内。根据暴露于122 keV伽马射线的制作探测器的泛光图,计算出峰谷(P/V)比大于2.3。P/V值表明,无论晶体厚度如何,像素均可分辨。

结论

结果表明,光学势垒可被视为机械像素化阵列的一种可靠替代方案,并且能够以高通量和经济高效的方式在保持灵敏度的同时提供高空间分辨率。

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