Osman Mai Abdel Raouf, Shokeir Hisham Ali, Fawzy Marwa M
*National Institute of Laser Enhanced Sciences, Cairo University, Cairo, Egypt; †Department of Dermatology, Faculty of Medicine, Cairo University, Cairo, Egypt.
Dermatol Surg. 2017 Jan;43 Suppl 1:S47-S56. doi: 10.1097/DSS.0000000000000951.
Ablative fractional erbium-doped yttrium aluminum garnet (Er:YAG) laser and microneedling have been popularized in recent years and their effectiveness and side effects individually reported. No previous study, however, has directly compared the efficacy and safety between the 2 different treatments.
To compare the efficacy and safety of the ablative fractional Er:YAG laser and microneedling for the treatment of atrophic acne scars.
Thirty patients with atrophic acne scars were randomly treated in a split-face manner with a fractional Er:YAG laser on one side and microneedling on the other side. All patients received 5 treatments with a 1-month interval. Objective and subjective assessments were obtained at baseline and at 3 months after the final treatment.
At the 3-month follow-up, both treatment modalities induced noticeable clinical and histological improvement, with significantly better results in fractional Er:YAG laser versus microneedling (70% vs 30%), respectively (p < .001). Fractional Er:YAG laser sides had significantly lower pain scores. Total downtime was significantly shorter in microneedling sides.
Both treatment modalities are effective and safe in the treatment of atrophic acne scars, with significantly higher scar response to the fractional Er:YAG laser treatment.
近年来，剥脱性点阵掺铒钇铝石榴石（Er:YAG）激光和微针治疗已得到普及，且分别报道了它们的有效性和副作用。然而，此前尚无研究直接比较这两种不同治疗方法的疗效和安全性。
比较剥脱性点阵Er:YAG激光和微针治疗萎缩性痤疮瘢痕的疗效和安全性。
30例萎缩性痤疮瘢痕患者采用半脸随机治疗，一侧接受点阵Er:YAG激光治疗，另一侧接受微针治疗。所有患者均接受5次治疗，间隔1个月。在基线和最后一次治疗后3个月进行客观和主观评估。
在3个月的随访中，两种治疗方式均引起了明显的临床和组织学改善，点阵Er:YAG激光治疗的效果明显优于微针治疗（分别为70%对30%）（p <.001）。点阵Er:YAG激光治疗侧的疼痛评分明显更低。微针治疗侧的总停工期明显更短。
两种治疗方式在治疗萎缩性痤疮瘢痕方面均有效且安全，点阵Er:YAG激光治疗的瘢痕反应明显更高。
