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[慢性躯体疾病中的疲劳]

[Fatigue in chronic physical diseases].

作者信息

Weis Joachim

机构信息

Tumorzentrum/Comprehensive Cancer Center Freiburg, Professur Selbsthilfeforschung, Medizinische Fakultät, Universität Freiburg, Hugstetter Str. 49, 79106, Freiburg, Deutschland.

出版信息

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2024 Nov;67(11):1231-1238. doi: 10.1007/s00103-024-03951-0. Epub 2024 Sep 16.

DOI:10.1007/s00103-024-03951-0
PMID:39284934
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11549205/
Abstract

The term fatigue is used to describe states of unusual tiredness and exhaustion that can occur in connection with various chronic diseases, particularly cancer, multiple sclerosis, Parkinson's disease and rheumatoid arthritis. In contrast to states of exhaustion in healthy people, fatigue is characterized by the fact that it can last for long periods, is disproportionate to previous activities and does not subside after recovery phases. Fatigue is described as a multidimensional problem that encompasses physical, emotional and cognitive aspects and is associated with a high level of subjective suffering. Depending on the severity and course of the symptoms, fatigue is associated with a severely reduced quality of life and it impairs participation and coping with everyday life. It also makes professional reintegration and reemployment more difficult. Although we cannot yet fully explain the aetiology and pathogenesis, fatigue in physical illnesses must be understood based on a multifactorial biopsychosocial model. The possibilities of diagnostics and an overview of various measures for clarifying fatigue are presented. The challenges for medical care are also outlined and advice is given on how to deal with them in everyday clinical practice.

摘要

“疲劳”一词用于描述与各种慢性疾病相关的异常疲倦和精疲力竭状态,尤其是癌症、多发性硬化症、帕金森病和类风湿性关节炎。与健康人的疲惫状态不同,疲劳的特点是可能持续很长时间,与之前的活动不相称,且在恢复阶段后不会消退。疲劳被描述为一个多维度问题,涵盖身体、情感和认知方面,并伴有高度的主观痛苦。根据症状的严重程度和病程,疲劳会导致生活质量严重下降,损害参与和应对日常生活的能力,还会使职业重新融入和再就业变得更加困难。尽管我们尚未完全解释其病因和发病机制,但身体疾病中的疲劳必须基于多因素生物心理社会模型来理解。本文介绍了疲劳的诊断方法以及各种用于明确疲劳的措施概述,还概述了医疗护理面临的挑战,并就如何在日常临床实践中应对这些挑战提供了建议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/598a/11549205/2a6218670f19/103_2024_3951_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/598a/11549205/5b2fcd2c42ce/103_2024_3951_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/598a/11549205/2a6218670f19/103_2024_3951_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/598a/11549205/5b2fcd2c42ce/103_2024_3951_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/598a/11549205/2a6218670f19/103_2024_3951_Fig2_HTML.jpg

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2023 EULAR recommendations for the management of fatigue in people with inflammatory rheumatic and musculoskeletal diseases.2023 年 EULAR 炎症性风湿和肌肉骨骼疾病患者疲劳管理建议。
Ann Rheum Dis. 2024 Sep 30;83(10):1260-1267. doi: 10.1136/ard-2023-224514.
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Measuring Fatigue in Multiple Sclerosis: There may be Trouble Ahead.多发性硬化症中的疲劳测量:前方可能有麻烦。
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Why Pheidippides could not believe in the 'Central Governor Model': Popper's philosophy applied to choose between two exercise physiology theories.
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Int J Environ Res Public Health. 2022 Mar 25;19(7):3909. doi: 10.3390/ijerph19073909.
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Cogn Affect Behav Neurosci. 2022 Apr;22(2):215-228. doi: 10.3758/s13415-021-00958-x. Epub 2021 Oct 19.
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Fatigue in inflammatory rheumatic diseases: current knowledge and areas for future research.炎症性风湿性疾病中的疲劳:当前的知识和未来研究领域。
Nat Rev Rheumatol. 2021 Nov;17(11):651-664. doi: 10.1038/s41584-021-00692-1. Epub 2021 Oct 1.
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Somatic symptoms in sleep disturbance.睡眠障碍中的躯体症状。
Psychol Health Med. 2023 Apr;28(4):884-894. doi: 10.1080/13548506.2021.1985149. Epub 2021 Sep 29.
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