固有淋巴细胞的演变。
The evolution of innate lymphoid cells.
作者信息
Vivier Eric, van de Pavert Serge A, Cooper Max D, Belz Gabrielle T
机构信息
Centre d'Immunologie de Marseille-Luminy, Aix-Marseille University UM2, Inserm, U1104, CNRS UMR7280, Marseille, France.
Hôpital de la Conception, Assistance Publique-Hôpitaux de Marseille, Marseille, France.
出版信息
Nat Immunol. 2016 Jun 21;17(7):790-4. doi: 10.1038/ni.3459.
Abstract
Innate lymphoid cells (ILCs) are the most recently discovered group of immune cells. Understanding their biology poses many challenges. We discuss here the current knowledge on the appearance of ILC subsets during evolution and propose how the connection between ILCs and T cells contributes to the robustness of immunity and hence to the fitness of the hosts.
摘要
固有淋巴细胞（ILC）是最近发现的一组免疫细胞。了解它们的生物学特性面临许多挑战。我们在此讨论关于ILC亚群在进化过程中出现的当前知识，并提出ILC与T细胞之间的联系如何有助于增强免疫的稳健性，从而有助于宿主的健康。
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