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菲律宾邦阿西楠部分原住民社区使用大戟草治疗登革热的民族药理学研究

Ethnopharmacological studies on the uses of Euphorbia hirta in the treatment of dengue in selected indigenous communities in Pangasinan (Philippines).

作者信息

de Guzman Gerard Quinto, Dacanay Aleth Therese Lora, Andaya Benjel Andaya, Alejandro Grecebio Jonathan Duran

机构信息

Cluster of Pharmacy and Medical Technology, The Graduate School, University of Santo Tomas, Manila, Philippines.

Department of Pharmacy, Faculty of Pharmacy, University of Santo Tomas, Manila, Philippines.

出版信息

J Intercult Ethnopharmacol. 2016 Apr 1;5(3):239-43. doi: 10.5455/jice.20160330124637. eCollection 2016 Jun-Aug.

Abstract

AIM

Euphorbia hirta is the most widely used plant in the folkloric treatment of dengue in the Philippines. This study documents the anecdotal uses of E. hirta in the treatment of dengue in 3 indigenous communities in Pangasinan from April to June of 2015.

MATERIALS AND METHODS

The number of use reports pertaining to symptoms of dengue and other diseases were tallied from 82 informants living in Anda Island, Mt. Colisao and Mt. Balungao. The demographics of the informants as well as the corrected major use agreements (cMUAs) and fidelity levels (FLs) of each reported symptom of dengue were calculated. The major dosage forms used during treatment were also tallied.

RESULTS

Respondents, dominated by the age group 60-80 and mostly females with at least primary and secondary education, provided information on the use reports of E. hirta. High FL values and cMUA of at least 35% were obtained for cardinal symptoms of dengue-related to bleeding episodes while low cMUAs (i.e. 2-4%) were obtained for symptoms during the recovery phase. High FL values were obtained for symptoms observed during the febrile phase. The most widely used dosage forms are decoctions of the leaves and barks of E. hirta.

CONCLUSION

This study was able to qualify the uses of E. hirta in the treatment of dengue in the 3 communities surveyed.

摘要

目的

在菲律宾,大戟是民间治疗登革热使用最为广泛的植物。本研究记录了2015年4月至6月间潘加锡南省3个土著社区使用大戟治疗登革热的传闻用法。

材料与方法

统计了安达岛、科利绍山和巴隆高山82位受访者关于登革热及其他疾病症状的使用报告数量。计算了受访者的人口统计学数据以及每种登革热报告症状的校正主要使用共识(cMUA)和可信度水平(FL)。还统计了治疗期间使用的主要剂型。

结果

受访者以60 - 80岁年龄组为主,大多为至少接受过小学和中学教育的女性,她们提供了大戟使用报告的信息。与出血事件相关的登革热主要症状获得了较高的FL值和至少35%的cMUA,而恢复期症状的cMUA较低(即2 - 4%)。发热期观察到的症状获得了较高的FL值。使用最广泛的剂型是大戟叶和树皮的煎剂。

结论

本研究明确了大戟在3个被调查社区治疗登革热方面的用途。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c13/4927128/883583f59ea7/JIE-5-239-g001.jpg

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