Ainsbury Elizabeth, Badie Christophe, Barnard Stephen, Manning Grainne, Moquet Jayne, Abend Michael, Antunes Ana Catarina, Barrios Lleonard, Bassinet Celine, Beinke Christina, Bortolin Emanuela, Bossin Lily, Bricknell Clare, Brzoska Kamil, Buraczewska Iwona, Castaño Carlos Huertas, Čemusová Zina, Christiansson Maria, Cordero Santiago Mateos, Cosler Guillaume, Monaca Sara Della, Desangles François, Discher Michael, Dominguez Inmaculada, Doucha-Senf Sven, Eakins Jon, Fattibene Paola, Filippi Silvia, Frenzel Monika, Georgieva Dimka, Gregoire Eric, Guogyte Kamile, Hadjidekova Valeria, Hadjiiska Ljubomira, Hristova Rositsa, Karakosta Maria, Kis Enikő, Kriehuber Ralf, Lee Jungil, Lloyd David, Lumniczky Katalin, Lyng Fiona, Macaeva Ellina, Majewski Matthaeus, Vanda Martins S, McKeever Stephen W S, Meade Aidan, Medipally Dinesh, Meschini Roberta, M'kacher Radhia, Gil Octávia Monteiro, Montero Alegria, Moreno Mercedes, Noditi Mihaela, Oestreicher Ursula, Oskamp Dominik, Palitti Fabrizio, Palma Valentina, Pantelias Gabriel, Pateux Jerome, Patrono Clarice, Pepe Gaetano, Port Matthias, Prieto María Jesús, Quattrini Maria Cristina, Quintens Roel, Ricoul Michelle, Roy Laurence, Sabatier Laure, Sebastià Natividad, Sholom Sergey, Sommer Sylwester, Staynova Albena, Strunz Sonja, Terzoudi Georgia, Testa Antonella, Trompier Francois, Valente Marco, Hoey Olivier Van, Veronese Ivan, Wojcik Andrzej, Woda Clemens
a Public Health England Centre for Radiation, Chemical and Environmental Hazards (PHE) , Chilton , UK.
b Bundeswehr Institute of Radiobiology (BIR) , Munich , Germany.
Int J Radiat Biol. 2017 Jan;93(1):99-109. doi: 10.1080/09553002.2016.1206233. Epub 2016 Jul 20.
RENEB, 'Realising the European Network of Biodosimetry and Physical Retrospective Dosimetry,' is a network for research and emergency response mutual assistance in biodosimetry within the EU. Within this extremely active network, a number of new dosimetry methods have recently been proposed or developed. There is a requirement to test and/or validate these candidate techniques and inter-comparison exercises are a well-established method for such validation.
The authors present details of inter-comparisons of four such new methods: dicentric chromosome analysis including telomere and centromere staining; the gene expression assay carried out in whole blood; Raman spectroscopy on blood lymphocytes, and detection of radiation-induced thermoluminescent signals in glass screens taken from mobile phones.
In general the results show good agreement between the laboratories and methods within the expected levels of uncertainty, and thus demonstrate that there is a lot of potential for each of the candidate techniques.
Further work is required before the new methods can be included within the suite of reliable dosimetry methods for use by RENEB partners and others in routine and emergency response scenarios.
RENE（“实现欧洲生物剂量测定与物理回顾性剂量测定网络”）是欧盟内部生物剂量测定研究与应急响应互助网络。在这个极为活跃的网络中，近期提出或开发了一些新的剂量测定方法。需要对这些候选技术进行测试和/或验证，而相互比较是进行此类验证的成熟方法。
作者介绍了四种此类新方法相互比较的详细情况：包括端粒和着丝粒染色的双着丝粒染色体分析；全血中的基因表达检测；血液淋巴细胞的拉曼光谱分析，以及从手机获取的玻璃屏中辐射诱导热释光信号的检测。
总体而言，结果显示各实验室和方法之间在预期不确定度水平内具有良好的一致性，从而表明每种候选技术都有很大潜力。
在新方法能够被纳入可靠剂量测定方法体系供RENE合作伙伴及其他机构在常规和应急响应场景中使用之前，还需要开展进一步工作。
