Sobrado Carlos Walter, Leal Raquel Franco, Sobrado Lucas Faraco
Disciplina de Coloproctologia, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (FMUSP), Brasil.
Departamento de Cirurgia, Unidade de Coloproctologia, Universidade de Campinas (UNICAMP), Brasil.
Arq Gastroenterol. 2016 Jul-Sep;53(3):206-11. doi: 10.1590/S0004-28032016000300016.
The main objectives of clinical therapy in Crohn's disease are clinical and endoscopic remission without the use of corticosteroids for long periods of time, prevention of hospitalization and surgery, and improvement of quality of life. The main limitation of drug therapy is the loss of response over the long term, which makes incorporation of new drugs to the therapeutic arsenal necessary. This review analyses the main drugs currently used in clinical treatment of Crohn's disease.
克罗恩病临床治疗的主要目标是实现临床和内镜缓解，且无需长期使用皮质类固醇，预防住院和手术，并提高生活质量。药物治疗的主要局限性在于长期疗效丧失，这使得有必要在治疗手段中加入新药。本综述分析了目前用于克罗恩病临床治疗的主要药物。
