Conner W T, Dolovich M B, Frame R A, Newhouse M T
Department of Pediatrics, St. Joseph's Hospital, McMaster University, Hamilton, Ontario, Canada.
Pediatr Pulmonol. 1989;6(4):263-7. doi: 10.1002/ppul.1950060410.
A double-blind study was performed to demonstrate that bronchodilator can be administered reliably to infants and children under 3 years of age from a metered-dose inhaler (MDI) by means of an economical valved aerosol-holding chamber device (Aerochamber) fitted with a mask. Symptoms of cough and breathlessness were compared for two 1-week crossover periods with the child either taking active drug or placebo. The MDI and Aerochamber with mask is an effective delivery system for respiratory therapy in these young children.
进行了一项双盲研究,以证明通过配备面罩的经济型带阀储雾罐装置(储物罐),可从定量吸入器(MDI)向3岁以下婴幼儿可靠地给药支气管扩张剂。在两个为期1周的交叉期内,比较了儿童服用活性药物或安慰剂时咳嗽和呼吸急促的症状。带面罩的MDI和储物罐是这些幼儿进行呼吸治疗的有效给药系统。