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中国女性超重/肥胖分布的城乡差异及其与乳腺癌的潜在趋势。

Urban-rural disparity of overweight/obesity distribution and its potential trend with breast cancer among Chinese women.

作者信息

Gao Ying, Huang Yubei, Song Fengju, Dai Hongji, Wang Peishan, Li Haixin, Zheng Hong, Dong Henglei, Han Jiali, Wang Yaogang, Chen Kexin

机构信息

Department of Health Service Management, School of Public Health, Tianjin Medical University, Tianjin, China.

Health Management Center, Tianjin Medical University General Hospital, Tianjin, China.

出版信息

Oncotarget. 2016 Aug 30;7(35):56608-56618. doi: 10.18632/oncotarget.10968.

Abstract

OBJECTIVE

To evaluate the urban-rural disparity of overweight/obesity and explore its potential trend with breast cancer among Chinese women.

RESULTS

The prevalence of overweight/obesity for Chinese rural women (35.2%, 29.2% for overweight and 6.0% for obesity) was significantly higher than that for Chinese urban women (33.4%, 27.7% for overweight and 5.7% for obesity) (P < 0.001). For either rural or urban women, the prevalence of overweight/obesity was highest in north region, followed by east region for rural women and north-east region for urban women. For rural women, higher prevalence of overweight/obesity was significantly positively associated with elder age, Han nationality, low level of education, no occupation, high family income, less number of family residents, insurance, and elder age at marriage. Similar positive associations were also found for urban women, except negative associations for high family income, less number of family residents, and elder age at marriage. A non-significant positive trend between overweight/obesity and breast cancer was found for rural women [odds ratio (OR): 1.06; 95% confidence interval (CI): 0.87-1.29], but a significant positive trend for urban women (OR: 1.55; 95% CI: 1.19-2.02).

MATERIALS AND METHODS

A total of 1 210 762 participants were recruited from the Chinese National Breast Cancer Screening Program. Overweight and obesity were defined as body mass index (BMI) ranged 24.0-27.9 kg/m2 and BMI ≥ 28.0kg/m2, respectively.

CONCLUSIONS

There was an obvious urban-rural disparity of overweight/obesity distribution among Chinese women, which could also lead to an obvious disparity of breast cancer distribution.

摘要

目的

评估中国女性超重/肥胖的城乡差异,并探讨其与乳腺癌潜在的关联趋势。

结果

中国农村女性超重/肥胖的患病率(超重为29.2%,肥胖为6.0%,总计35.2%)显著高于中国城市女性(超重为27.7%,肥胖为5.7%,总计33.4%)(P<0.001)。对于农村和城市女性,超重/肥胖患病率在北方地区最高,农村女性其次是东部地区,城市女性其次是东北地区。对于农村女性,超重/肥胖患病率较高与年龄较大、汉族、教育程度低、无职业、家庭收入高、家庭居住人数少、参保以及结婚年龄较大显著正相关。城市女性也发现了类似的正相关,但家庭收入高、家庭居住人数少和结婚年龄较大呈负相关。农村女性超重/肥胖与乳腺癌之间存在不显著的正相关趋势[比值比(OR):1.06;95%置信区间(CI):0.87 - 1.29],但城市女性存在显著的正相关趋势(OR:1.55;95%CI:1.19 - 2.02)。

材料与方法

从中国国家乳腺癌筛查项目中招募了总共1210762名参与者。超重和肥胖分别定义为体重指数(BMI)在24.0 - 27.9kg/m²和BMI≥28.0kg/m²。

结论

中国女性超重/肥胖分布存在明显的城乡差异,这也可能导致乳腺癌分布的明显差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b316/5302938/3f87e9e071f2/oncotarget-07-56608-g001.jpg

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