Lee Sang-Woon, Kim Seong-Gon
Department of Oral and Maxillofacial Surgery, Gangneung Asan Hospital, Gangneung-Wonju National University.
Maxillofac Plast Reconstr Surg. 2014 Nov;36(6):239-46. doi: 10.14402/jkamprs.2014.36.6.239. Epub 2014 Nov 12.
Many kinds of membrane have been used for the guided bone regeneration (GBR) technique. However, most membranes do not fulfill all requirements for the ideal membrane for the GBR technique. Among them, collagen membrane has been most widely used. However, its high price and weak tensile strength in wet condition are limitations for wide clinical application. Synthetic polymers have also been used for the GBR technique. Recently, silk based membrane has been considered as a membrane for the GBR technique. Despite many promising preclinical data for use of a silk membrane, clinical data regarding the silk membrane has been limited. However, silk based material has been used clinically as vessel-tie material and an electrospun silk membrane was applied successfully to patients. No adverse effect related to the silk suture has been reported. Considering that silk membrane can be provided to patients at a cheap price, its clinical application should be encouraged.
许多种膜已被用于引导骨再生（GBR）技术。然而，大多数膜并不能满足GBR技术理想膜的所有要求。其中，胶原膜应用最为广泛。然而，其高价格以及在潮湿条件下较弱的拉伸强度限制了其在临床上的广泛应用。合成聚合物也已用于GBR技术。最近，丝基膜被认为是一种用于GBR技术的膜。尽管丝膜使用的临床前数据很有前景，但关于丝膜的临床数据却很有限。然而，丝基材料已在临床上用作血管结扎材料，并且一种电纺丝膜已成功应用于患者。尚未有与丝缝线相关的不良反应报道。鉴于丝膜可以以低廉的价格提供给患者，应鼓励其临床应用。
