Cesari Matteo, Marzetti Emanuele, Canevelli Marco, Guaraldi Giovanni
a Gérontopôle , Centre Hospitalier Universitaire de Toulouse , Toulouse , France.
b Université de Toulouse III Paul Sabatier , Toulouse , France.
Virulence. 2017 Jul 4;8(5):577-585. doi: 10.1080/21505594.2016.1219445. Epub 2016 Aug 11.
The survival of HIV-infected persons has been increasing over the last years, thanks to the implementation of more effective pharmacological and non-pharmacological interventions. Nevertheless, HIV-infected persons are often "biologically" older than their "chronological" age due to multiple clinical, social, and behavioral conditions of risk. The detection in this population of specific biological features and syndromic conditions typical of advanced age has made the HIV infection an interesting research model of accelerated and accentuated aging. Given such commonalities, it is possible that "biologically aged" HIV-positive persons might benefit from models of adapted and integrated care developed over the years by geriatricians for the management of their frail and complex patients. In this article, possible strategies to face the increasingly prevalent geriatric syndromes in HIV-infected persons are discussed. In particular, it is explained the importance of shifting from the traditional disease-oriented approach into models of care facilitating a multidisciplinary management of frailty.
在过去几年中，由于实施了更有效的药物和非药物干预措施，艾滋病毒感染者的生存率一直在提高。然而，由于多种临床、社会和行为风险因素，艾滋病毒感染者的“生物学年龄”往往比其“实际年龄”更大。在这一人群中检测到典型的老年特定生物学特征和综合征，使得艾滋病毒感染成为加速和加剧衰老的一个有趣研究模型。鉴于这些共性，“生物学年龄较大”的艾滋病毒阳性者可能会受益于老年医学专家多年来开发的适用于体弱多病和复杂患者管理的适应性综合护理模式。在本文中，讨论了应对艾滋病毒感染者中日益普遍的老年综合征的可能策略。特别是，解释了从传统的以疾病为导向的方法转向促进对体弱多病进行多学科管理的护理模式的重要性。
