Ingoldby C J, el-Saadi J, Hall R I, Denyer M E
University Department of Surgery, St James's University Hospital, Leeds.
Gut. 1989 Aug;30(8):1129-31. doi: 10.1136/gut.30.8.1129.
Endoscopic sphincterotomy was undertaken in 186 patients with common bile duct stones and an intact gall bladder who were considered unfit for surgery. One hundred and seventy one patients had jaundice of whom 18 also had clinical cholangitis. The mean age of treated patients was 79.7 years (range 27-92) and only 13 were aged less than 60. Sphincterotomy was successful in 185 (99%) and complete clearance achieved in 172 (92.5%). Early complications occurred in nine patients (4.8%) of whom three died (1.6%). The patients have been followed on average for 32 months (range six to 72 months). Eighteen patients have subsequently required cholecystectomy (9.6%), with six major complications, but no deaths. There have been 27 natural deaths and 156 patients remain alive and symptom free. Endoscopic treatment alone is safe and effective in the majority of frail and elderly patients and can reduce the need for surgery in this high risk group.
对186例被认为不宜进行手术的胆总管结石且胆囊完好的患者实施了内镜括约肌切开术。171例患者有黄疸,其中18例还伴有临床胆管炎。接受治疗患者的平均年龄为79.7岁(范围27 - 92岁),只有13例年龄小于60岁。括约肌切开术成功185例(99%),结石完全清除172例(92.5%)。9例患者(4.8%)出现早期并发症,其中3例死亡(1.6%)。患者平均随访32个月(范围6至72个月)。18例患者随后需要进行胆囊切除术(9.6%),出现6例严重并发症,但无死亡病例。有27例自然死亡,156例患者仍存活且无症状。对于大多数体弱和老年患者,单纯内镜治疗是安全有效的,并且可以减少这一高危群体的手术需求。