Andrada-Serpa M J, Tosswill J, Schor D, Linhares D, Dobbin J, Pereira M S
Basic Research Center, National Cancer Institute, Rio de Janeiro, Brazil.
Int J Cancer. 1989 Sep 15;44(3):389-93. doi: 10.1002/ijc.2910440302.
The prevalence of antibodies to HTLV-I and HIV-I in Brazil was determined by testing sera from: (a) 119 members of an isolated Amazonian community of African origin; (b) 100 voluntary blood donors in Rio de Janeiro; (c) 215 patients treated at the Hematology Service, National Cancer Institute, Rio de Janeiro, and (d) 44 Cebus apella New World monkeys, wild-caught in Amazonia. Anti-HTLV-I was detected in 1 (0.84%) of 119 Amazonians, in 8 (3.72%) of the 215 patients and in none of the blood donors or monkeys. The high prevalence found in patients included 4 (5.79%) of 69 with non-Hodgkin lymphoma, 2 (5.88%) of 34 with Hodgkin lymphoma, 1 (16.66%) of 6 patients with diagnosis of anemia and 1 (20%) of 5 with HIV-I infection. Anti-HIV-I was found in 7 (14.89%) of 47 patients and in none of the other groups. The high incidence of HTLV-I infection in the patient group suggests that this retrovirus is endemic in parts of Brazil.
通过检测以下人群的血清，确定了巴西人群中抗人类嗜T淋巴细胞病毒I型（HTLV-I）和抗人类免疫缺陷病毒I型（HIV-I）的流行情况：（a）一个与世隔绝的非洲裔亚马逊社区的119名成员；（b）里约热内卢的100名自愿献血者；（c）在里约热内卢国家癌症研究所血液科接受治疗的215名患者；（d）在亚马逊地区野生捕获的44只新世界僧帽猴。在119名亚马逊人中，有1人（0.84%）检测出抗HTLV-I；在215名患者中，有8人（3.72%）检测出抗HTLV-I；而在献血者和猴子中均未检测到。在患者中发现的高流行率包括：69名非霍奇金淋巴瘤患者中有4人（5.79%）、34名霍奇金淋巴瘤患者中有2人（5.88%）、诊断为贫血的6名患者中有1人（16.66%）以及5名HIV-I感染患者中有1人（20%）。在47名患者中，有7人（14.89%）检测出抗HIV-I，其他组均未检测到。患者组中HTLV-I感染的高发病率表明，这种逆转录病毒在巴西部分地区呈地方性流行。
