Holla Vidya A, Chatra L K, Shenai Prashanth, Shetty Devika, Baliga Ashwini
A J Institute of Dental Sciences, Mangalore, India.
Department of Oral Medicine and Radiology, Yenepoya Dental College, Mangalore, India.
Adv Med. 2016;2016:6124059. doi: 10.1155/2016/6124059. Epub 2016 Sep 29.
. Oral submucous fibrosis (OSF) is a potentially malignant disorder associated with the usage of areca nut. Usage of processed forms of areca nut is popular among the youth and its carcinogenic effects are not well known. Due to large immigrant population, various patterns of areca nut usage are seen. The aim of this study is to assess the various quid chewing patterns and their association with severity of OSF. . A cross-sectional study was carried out with 250 cases clinically and histologically diagnosed as having OSF lesion that were selected and subjected to a detailed habit history which was recorded through preformed questionnaire. The data obtained was statistically analyzed. . Among the 250 subjects, males were seen to be affected more than females within the age group of 26-35 years and were having clinical stage I OSF. A combination of processed areca nut and processed tobacco was used by the majority of the subjects with duration of 1 to 5 years, at a frequency of 3 to 5 quids per day. . The present study confirms the association between oral submucous fibrosis and the quid containing processed areca nut and processed tobacco and also highlights the increasing youth population using the processed forms of areca nut.
口腔黏膜下纤维化（OSF）是一种与槟榔使用相关的潜在恶性疾病。加工形式的槟榔在年轻人中很受欢迎，其致癌作用尚不为人所知。由于大量移民人口，出现了各种槟榔使用模式。本研究的目的是评估各种嚼块咀嚼模式及其与OSF严重程度的关联。
对250例临床和组织学诊断为患有OSF病变的病例进行了横断面研究，这些病例被选中并通过预先设计的问卷记录详细的习惯史。对获得的数据进行了统计分析。
在250名受试者中，26至35岁年龄组内男性受影响的人数多于女性，且处于临床I期OSF。大多数受试者使用加工槟榔和加工烟草的组合，持续时间为1至5年，每天咀嚼3至5块。
本研究证实了口腔黏膜下纤维化与含有加工槟榔和加工烟草的嚼块之间的关联，也突出了使用加工形式槟榔的青年人群不断增加的情况。
