Karaca Emine Esra, Akçam Hanife Tuba, Uzun Feyzahan, Özdek Şengül, Ulukavak Çiftçi Tansu
Sorgun State Hospital, Ophthalmology Clinic, Yozgat, Turkey.
Çankırı State Hospital, Ophthalmology Clinic, Çankırı, Turkey.
Turk J Ophthalmol. 2016 Jun;46(3):104-108. doi: 10.4274/tjo.57778. Epub 2016 Jun 6.
To evaluate ocular surface health in obstructive sleep apnea syndrome (OSAS) and to investigate the tendency of these patients toward dry eyes.
Fifty patients who underwent polysomnography and were diagnosed with OSAS and 50 normal control subjects were compared with respect to ocular surface disease index (OSDI), Schirmer I test and tear film break-up time (TBUT) values.
Patients were grouped as mild (n=15, 30%), moderate (n=15, 30%) and severe (n=20, 40%) according to apnea-hypopnea index values. The right eyes of patients were included in both groups. OSDI values were as follows: control group, 18.7±8.5; mild OSAS group, 40.2±2.8; moderate OSAS group, 48.5±2.2 and severe OSAS group, 62.7±2.3 (p<0.001). TBUT values were as follows: control group, 12.3±4.9; mild OSAS group, 8.2±4.7; moderate OSAS group, 5.8±2.1 and severe OSAS group, 4.2±3.7 (p<0.001). Schirmer values were as follows: control group, 18±6.1 mm; mild OSAS group, 12.9±6.7 mm; moderate OSAS group, 8.5±5.2 mm and severe OSAS group, 7.9±4.7 mm (p<0.001).
Patients with OSAS seem to have a tendency toward dry eyes. Clinicians should be aware of dry eye development in these patients.
评估阻塞性睡眠呼吸暂停综合征（OSAS）患者的眼表健康状况，并调查这些患者发生干眼的倾向。
将50例行多导睡眠图检查并诊断为OSAS的患者与50名正常对照者进行比较，比较指标包括眼表疾病指数（OSDI）、泪液分泌试验I（Schirmer I test）和泪膜破裂时间（TBUT）值。
根据呼吸暂停低通气指数值，将患者分为轻度组（n = 15，30%）、中度组（n = 15，30%）和重度组（n = 20，40%）。两组均纳入患者的右眼数据。OSDI值如下：对照组为18.7±8.5；轻度OSAS组为40.2±2.8；中度OSAS组为48.5±2.2；重度OSAS组为62.7±2.3（p<0.001）。TBUT值如下：对照组为12.3±4.9；轻度OSAS组为8.2±4.7；中度OSAS组为5.8±2.1；重度OSAS组为4.2±3.7（p<0.001）。Schirmer值如下：对照组为18±6.1mm；轻度OSAS组为12.9±6.7mm；中度OSAS组为8.5±5.2mm；重度OSAS组为7.9±4.7mm（p<0.001）。
OSAS患者似乎有发生干眼的倾向。临床医生应注意这些患者中干眼的发生情况。
