• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

痛风石性痛风导致腰椎管狭窄:一例报告。

Tophaceous gout causing lumbar stenosis: A case report.

作者信息

Lu Huigen, Sheng Jianming, Dai Jiaping, Hu Xuqi

机构信息

Department of Orthopaedics, The Second Hospital of Jiaxing, Jiaxing, China.

出版信息

Medicine (Baltimore). 2017 Aug;96(32):e7670. doi: 10.1097/MD.0000000000007670.

DOI:10.1097/MD.0000000000007670
PMID:28796049
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5556215/
Abstract

RATIONALE

Gout in the spine is very rare. The clinical symptoms of the spinal gout are various and lack of specificity. The authors report a case of spinal gout causing lumbar stenosis. We never find such wide-invasive spinal gouty lesion in the published studies.

PATIENT CONCERNS

A 68-year-old male had low back pain radiating to bilateral lower limbs, accompanying with intermittent claudication that lasted for 3 months and aggravated 5 days ago.

DIAGNOSES

Spinal gout, lumbar stenosis.

INTERVENTIONS

The patient underwent L2-L4 laminectomy, L2/3 L3/4 an d L4/5 discectomy and transforaminal lumbar interbody fusion with pedicle screw fixation.

OUTCOMES

Dual-energy computed tomography detected extensive tophaceous deposits in L1/2 L2/3 L3/4 and L4/5 lumbar discs as well as the posterior column, especially L2-L3 and L4-L5 facet joints. During the surgery, we found a mass of chalky white material at the posterior column of L3 to L5 vertebral bodies, which also involved the intervertebral discs. Pathological examination confirmed the diagnosis of spinal gout.

LESSONS

Although spinal gout is thought to be rare, the diagnosis should be considered if the patient had severe back pain and a history of gout. Dual-energy computed tomography is highly recommended for these patients.

摘要

原理

脊柱痛风非常罕见。脊柱痛风的临床症状多样且缺乏特异性。作者报告了一例导致腰椎管狭窄的脊柱痛风病例。在已发表的研究中,我们从未发现如此广泛侵袭性的脊柱痛风性病变。

患者情况

一名68岁男性出现下背部疼痛并放射至双侧下肢,伴有间歇性跛行,持续3个月,5天前加重。

诊断

脊柱痛风,腰椎管狭窄。

干预措施

患者接受了L2-L4椎板切除术、L2/3、L3/4和L4/5椎间盘切除术以及经椎间孔腰椎椎体间融合术并椎弓根螺钉固定。

结果

双能计算机断层扫描在L1/2、L2/3、L3/4和L4/5腰椎间盘以及后柱,尤其是L2-L3和L4-L5小关节处检测到广泛的痛风石沉积。手术中,我们在L3至L5椎体的后柱发现了一团灰白色物质,其也累及椎间盘。病理检查证实了脊柱痛风的诊断。

经验教训

尽管脊柱痛风被认为很罕见,但如果患者有严重的背痛和痛风病史,应考虑进行诊断。强烈建议对这些患者进行双能计算机断层扫描。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/589e/5556215/86a6adbc5030/medi-96-e7670-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/589e/5556215/134325b03aaa/medi-96-e7670-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/589e/5556215/a961125a0d87/medi-96-e7670-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/589e/5556215/5f61bb961cd4/medi-96-e7670-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/589e/5556215/86a6adbc5030/medi-96-e7670-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/589e/5556215/134325b03aaa/medi-96-e7670-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/589e/5556215/a961125a0d87/medi-96-e7670-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/589e/5556215/5f61bb961cd4/medi-96-e7670-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/589e/5556215/86a6adbc5030/medi-96-e7670-g004.jpg

相似文献

1
Tophaceous gout causing lumbar stenosis: A case report.痛风石性痛风导致腰椎管狭窄:一例报告。
Medicine (Baltimore). 2017 Aug;96(32):e7670. doi: 10.1097/MD.0000000000007670.
2
Percutaneous transforaminal endoscopic decompression for the treatment of intraspinal tophaceous gout: A case report.经皮椎间孔镜下减压治疗脊柱内痛风石:一例报告。
Medicine (Baltimore). 2020 May 22;99(21):e20125. doi: 10.1097/MD.0000000000020125.
3
Tophaceous gout of the lumbar spine mimicking a spinal meningioma.腰椎痛风石性痛风酷似脊膜瘤。
Eur Spine J. 2018 Apr;27(4):815-819. doi: 10.1007/s00586-016-4831-7. Epub 2016 Nov 5.
4
Lumbar spinal stenosis induced by rare chronic tophaceous gout in a 29-year-old man.一名29岁男性因罕见的慢性痛风石性痛风导致腰椎管狭窄。
Orthopedics. 2012 Oct;35(10):e1571-5. doi: 10.3928/01477447-20120919-33.
5
Gouty spondylodiscitis with lumbar vertebral body retrolisthesis: A case report.痛风性脊椎椎间盘炎伴腰椎椎体后滑脱:一例报告
Medicine (Baltimore). 2019 Feb;98(7):e14415. doi: 10.1097/MD.0000000000014415.
6
[Two different fixation methods combined with lumbar interbody fusion for the treatment of two-level lumbar vertebra diseases: a clinical comparison study].[两种不同固定方法联合腰椎椎间融合术治疗两节段腰椎疾病的临床对比研究]
Zhongguo Gu Shang. 2015 Oct;28(10):903-9.
7
Recurrent spinal stenosis caused by tophaceous gout: a case report and review of literature.痛风石性痛风所致复发性椎管狭窄:1例报告并文献复习
Changgeng Yi Xue Za Zhi. 1996 Sep;19(3):272-6.
8
Rigid, semirigid versus dynamic instrumentation for degenerative lumbar spinal stenosis: a correlative radiological and clinical analysis of short-term results.退行性腰椎管狭窄症的刚性、半刚性与动态内固定:短期结果的相关影像学与临床分析
Spine (Phila Pa 1976). 2004 Apr 1;29(7):735-42. doi: 10.1097/01.brs.0000112072.83196.0f.
9
Lumbar radiculopathy secondary to gouty tophi in the filum terminale in a patient without systemic gout: case report.一例无全身性痛风患者终丝痛风石继发腰椎神经根病:病例报告
Neurosurgery. 2000 Apr;46(4):986-8. doi: 10.1097/00006123-200004000-00042.
10
Tophaceous gout causing thoracic spinal cord compression: Case report and review of the literature.痛风石性痛风致胸段脊髓压迫症:病例报告及文献复习
Neurochirurgie. 2018 Jun;64(3):171-176. doi: 10.1016/j.neuchi.2017.11.002. Epub 2018 May 3.

引用本文的文献

1
Understanding spinal gout: A comprehensive study of 88 cases and their clinical implications.了解脊柱痛风:88例病例的综合研究及其临床意义。
J Craniovertebr Junction Spine. 2024 Apr-Jun;15(2):133-140. doi: 10.4103/jcvjs.jcvjs_166_23. Epub 2024 May 24.
2
Extravertebral low back pain: a scoping review.椎外下腰痛:范围综述。
BMC Musculoskelet Disord. 2024 May 7;25(1):363. doi: 10.1186/s12891-024-07435-9.
3
Intraspinal extradural gout tophus in the lumbar vertebral canal: Case reports.腰椎管内硬膜外痛风石:病例报告。

本文引用的文献

1
Tophaceous gout of the lumbar spine mimicking a spinal meningioma.腰椎痛风石性痛风酷似脊膜瘤。
Eur Spine J. 2018 Apr;27(4):815-819. doi: 10.1007/s00586-016-4831-7. Epub 2016 Nov 5.
2
Dual-Energy CT of Urate Deposits in Costal Cartilage and Intervertebral Disks of Patients With Tophaceous Gout and Age-Matched Controls.痛风石性痛风患者与年龄匹配对照者肋软骨和椎间盘尿酸盐沉积的双能CT研究
AJR Am J Roentgenol. 2016 May;206(5):1063-7. doi: 10.2214/AJR.15.15356. Epub 2016 Mar 9.
3
Gout in the Spine: Imaging, Diagnosis, and Outcomes.
Medicine (Baltimore). 2022 Jan 7;101(1):e28418. doi: 10.1097/MD.0000000000028418.
4
Tophaceous gout of the atlantoaxial joint: a case report.寰枢关节痛风石性痛风:一例报告
J Med Case Rep. 2021 Feb 15;15(1):74. doi: 10.1186/s13256-020-02638-9.
5
Beyond Medical Treatment: Surgical Treatment of Gout.超越医疗:痛风的手术治疗。
Curr Rheumatol Rep. 2020 Nov 24;23(1):1. doi: 10.1007/s11926-020-00969-6.
6
Systemic Urate Deposition: An Unrecognized Complication of Gout?全身尿酸沉积:痛风一种未被认识的并发症?
J Clin Med. 2020 Oct 3;9(10):3204. doi: 10.3390/jcm9103204.
7
Diagnostic advances in synovial fluid analysis and radiographic identification for crystalline arthritis.滑液分析和晶体性关节炎放射学鉴定的诊断进展。
Curr Opin Rheumatol. 2019 Mar;31(2):134-143. doi: 10.1097/BOR.0000000000000582.
脊柱痛风:影像学、诊断及预后
Curr Rheumatol Rep. 2015 Dec;17(12):70. doi: 10.1007/s11926-015-0547-7.
4
Urate crystal deposition in asymptomatic hyperuricaemia and symptomatic gout: a dual energy CT study.无症状高尿酸血症和有症状痛风患者尿酸盐晶体沉积:一项双能量 CT 研究。
Ann Rheum Dis. 2015 May;74(5):908-11. doi: 10.1136/annrheumdis-2014-206397. Epub 2015 Jan 30.
5
Imaging modalities for the classification of gout: systematic literature review and meta-analysis.痛风分类的影像学检查方法:系统文献综述与荟萃分析
Ann Rheum Dis. 2015 Oct;74(10):1868-74. doi: 10.1136/annrheumdis-2014-205431. Epub 2014 Jun 10.
6
Prevalence of gout and hyperuricemia in the US general population: the National Health and Nutrition Examination Survey 2007-2008.美国普通人群中痛风和高尿酸血症的患病率:2007 - 2008年国家健康与营养检查调查
Arthritis Rheum. 2011 Oct;63(10):3136-41. doi: 10.1002/art.30520.
7
Tophaceous gout of the odontoid process causing glossopharyngeal, vagus, and hypoglossal nerve palsies.齿状突痛风导致的咽舌、迷走和舌下神经麻痹。
Int J Rheum Dis. 2011 Feb;14(1):105-8. doi: 10.1111/j.1756-185X.2010.01565.x. Epub 2010 Aug 30.
8
[Fever and back pain--a case report of spinal gout].[发热与背痛——一例脊柱痛风病例报告]
Dtsch Med Wochenschr. 2010 Jan;135(4):125-8. doi: 10.1055/s-0029-1244828. Epub 2010 Jan 25.
9
Axial gouty arthropathy.轴性痛风性关节病
Am J Med Sci. 2009 Aug;338(2):140-6. doi: 10.1097/MAJ.0b013e3181a3dc14.
10
Gout in the axial skeleton.中轴骨骼痛风
J Rheumatol. 2009 Mar;36(3):609-13. doi: 10.3899/jrheum.080374. Epub 2009 Feb 4.