Song Qiaofeng, Liu Xiaoxue, Zhou Wenhua, Wang Xizhu, Wu Shouling
Department of Cardiology, Tangshan People's Hospital Department of Cardiology, Kailuan Hospital, North China University of Science and Technology, Tangshan, China.
Medicine (Baltimore). 2016 Nov;95(45):e5363. doi: 10.1097/MD.0000000000005363.
Evidence suggests short or long sleep duration is associated with a higher risk of diabetes. Using a large longitudinal data set spanning 2 years, we examined whether a change in sleep duration is associated with diabetes.Current analysis included 56,588 participants who were free of diabetes during both 2006-2007 (exam1) and 2008-2009 (exam2). Sleep duration was categorized into 7 groups: ≤5.5 hours, 6.0 to 6.5 hours, 7.0 hours, 7.5 to 8.0 hours, ≥8.5 hours, decrease ≥2 hours, and increase ≥2 hours. Cox proportional hazards models were used to calculate hazard ratios (HRs) and their confidence intervals (CI) for diabetes, according to sleep duration.Compared to the reference group of persistent 7-h sleepers, participants who slept 7.5 to 8 hours per night (HR, 1.20; 95% CI, 1.02-1.40), ≥8.5 hours per night (HR, 1.37; 95% CI, 1.03-1.81) and an increase of ≥2 hours sleep per night (HR, 1.24; 95% CI, 1.05-1.48) were all associated with an increased risk of developing diabetes in analyses adjusted for age, sex, education level, income level, smoking status, drinking status, physical activity, BMI, snoring status, hypertension, hyperlipidemia, and family history of diabetes. The abovementioned associations of sleep duration and incident diabetes were only prominent among individuals aged <64 years.This study suggests that individuals whose sleep duration increases ≥2 hours per night are at an increased risk of diabetes.
有证据表明,睡眠时间过短或过长都与患糖尿病的风险较高有关。我们使用一个跨度为2年的大型纵向数据集,研究了睡眠时间的变化是否与糖尿病有关。当前分析纳入了56588名在2006 - 2007年(检查1)和2008 - 2009年(检查2)期间均无糖尿病的参与者。睡眠时间被分为7组:≤5.5小时、6.0至6.5小时、7.0小时、7.5至8.0小时、≥8.5小时、减少≥2小时以及增加≥2小时。根据睡眠时间,使用Cox比例风险模型计算糖尿病的风险比(HRs)及其置信区间(CI)。与持续每晚睡7小时的参照组相比,在对年龄、性别、教育水平、收入水平、吸烟状况、饮酒状况、身体活动、体重指数、打鼾状况、高血压、高脂血症和糖尿病家族史进行调整的分析中,每晚睡7.5至8小时(HR,1.20;95%CI,1.02 - 1.40)、≥8.5小时(HR,1.37;95%CI,1.03 - 1.81)以及每晚睡眠时间增加≥2小时(HR,1.24;95%CI,1.05 - 1.48)的参与者患糖尿病的风险均增加。上述睡眠时间与糖尿病发病之间的关联仅在年龄<64岁的个体中显著。这项研究表明,每晚睡眠时间增加≥2小时的个体患糖尿病的风险增加。