Oshika T, Nishi M, Mochizuki M, Nakamura M, Kawashima H, Iwase K, Sawa M
Department of Ophthalmology, Tokyo Kosei Nenkin Hospital, Japan.
Jpn J Ophthalmol. 1989;33(3):279-87.
Validity of the laser flare-cell meter in uveitis was evaluated. A comparative study of slit-lamp examination and flare-cell meter measurements was carried out in the evaluation of iridocyclitis in a total of 251 measurements in patients with uveitis of various etiologies, including Behçet's disease, Vogt-Koyanagi-Harada's disease and sarcoidosis. The data obtained by these two methods showed a significant overall correlation both in the measurement of flare intensity (Kendall tau = 0.580, P less than 0.001) and cell count (tau = 0.390, P less than 0.001). Problems inherent to the slit-lamp examination were marked in terms of wide variations in grading within groups and large overlaps in scores between groups. The flare-cell meter was highly reliable in the measurement of flare intensity; whereas it could not detect low numbers of cells in some cases. Ninety-one eyes of patients with Behçet's disease were divided into three groups based on the interval from the last ocular attack episode. The flare-cell meter examination revealed that values for flare intensity remained abnormally high even in patients free from an attack episode for more than six months prior to the examination. It was considered that deterioration or breakdown of the blood-aqueous barrier function persists in patients with Behçet's disease.
对激光光斑细胞仪在葡萄膜炎中的有效性进行了评估。在对包括贝赫切特病、伏格特-小柳-原田病和结节病等各种病因的葡萄膜炎患者进行虹膜睫状体炎评估时，开展了裂隙灯检查与光斑细胞仪测量的对比研究。通过这两种方法获得的数据显示，在光斑强度测量（肯德尔tau系数=0.580，P<0.001）和细胞计数（tau系数=0.390，P<0.001）方面，总体具有显著相关性。裂隙灯检查所固有的问题表现为组内分级差异大以及组间评分重叠大。光斑细胞仪在光斑强度测量方面高度可靠；然而，在某些情况下它无法检测到少量细胞。将91例贝赫切特病患者的眼睛根据距上次眼部发作事件的间隔时间分为三组。光斑细胞仪检查显示，即使在检查前六个月以上无发作事件的患者中，光斑强度值仍异常高。认为贝赫切特病患者存在血-房水屏障功能的恶化或破坏。
