Jonas J B, Nguyen N X, Naumann G O
Department of Ophthalmology, University of Erlangen-Nurnberg, FRG.
Acta Ophthalmol (Copenh). 1989 Aug;67(4):361-6. doi: 10.1111/j.1755-3768.1989.tb01615.x.
Glaucoma is associated with changes of the optic disc topography. Using color stereo photographs we examined non-quantitative signs in 584 optic discs of 308 patients with chronic primary open-angle glaucoma and in 383 optic discs of 236 age and refraction matched normal subjects. Only one eye per patient and normal subject was chosen for statistical analysis. Highest predictive value to differentiate between normal and glaucoma eyes had the parameters 'changes in the juxtapapillary retinal nerve fiber layers' (86.7%), 'abnormal size (79.8%) and abnormal location (68.6%) of the parapapillary chorio-retinal atrophy', 'smallest neuroretinal rim part outside of the temporal horizontal disc sector' (78.5%), and area with cupping larger than area with pallor' (68.2%). Characteristics with high specificity and low sensitivity were 'optic disc haemorrhages', 'bared cilioretinal arteries', and 'bared circumlinear vessels'. With their evaluation being independent of sophisticated techniques the non-quantitative parameters are helpful for the ad hoc diagnosis of glaucomatous optic nerve damage.
青光眼与视盘地形图的改变相关。我们使用彩色立体照片检查了308例慢性原发性开角型青光眼患者的584个视盘以及236例年龄和屈光相匹配的正常受试者的383个视盘的非定量体征。每位患者和正常受试者仅选择一只眼睛进行统计分析。鉴别正常眼和青光眼眼的最高预测价值参数为“视盘旁视网膜神经纤维层改变”（86.7%）、“视盘旁脉络膜视网膜萎缩的异常大小（79.8%）和异常位置（68.6%）”、“颞侧水平视盘扇形区域外最小的神经视网膜边缘部分”（78.5%）以及“杯盘比大于苍白区面积”（68.2%）。高特异性和低敏感性的特征为“视盘出血”、“裸露的睫状视网膜动脉”和“裸露的环形血管”。这些非定量参数的评估无需复杂技术，有助于青光眼性视神经损伤的即时诊断。
