Jonas J B, Nguyen N X, Naumann G O
Department of Ophthalmology, University of Erlangen - Nürnberg, FRG.
Acta Ophthalmol (Copenh). 1989 Apr;67(2):199-203. doi: 10.1111/j.1755-3768.1989.tb00753.x.
This study was undertaken to evaluate the optic disc changes in eyes with non-glaucomatous optic nerve damage. The intra- and parapapillary region was evaluated morphometrically in 106 eyes of 56 patients with simple optic nerve atrophy (SONA) and in 107 normal eyes of 57 subjects. Colour stereo optic disc diapositives were used. Only one randomly chosen eye per subject and patient was taken for statistical analysis. Characteristics of SONA were: decreased visibility of the parapapillary retinal nerve fibers, diminished retinal vessel diameter, and area with pallor larger than area with cupping. Size and form of the optic disc, neuroretinal rim, peripapillary scleral ring, and zone Alpha and Beta of the parapillary chorioretinal atrophy were not significantly different. Also, distinctness of a tesselated fundus, frequency of optic disc haemorrhages and frequency of bared circumlinear or bared cilioretinal vessels did not differ significantly. These morphologic features are helpful in the diagnosis and differential diagnosis of SONA.
本研究旨在评估非青光眼性视神经损伤患者眼睛的视盘变化。对56例单纯性视神经萎缩（SONA）患者的106只眼睛和57名受试者的107只正常眼睛的视盘内及视盘旁区域进行了形态学评估。使用了彩色立体视盘幻灯片。每位受试者和患者仅随机选取一只眼睛进行统计分析。SONA的特征包括：视盘旁视网膜神经纤维可见度降低、视网膜血管直径减小以及苍白区域大于杯状凹陷区域。视盘的大小和形态、神经视网膜边缘、视盘周围巩膜环以及视盘旁脉络膜视网膜萎缩的α区和β区无显著差异。此外，镶嵌状眼底的清晰度、视盘出血频率以及裸露的环形或睫状视网膜血管频率也无显著差异。这些形态学特征有助于SONA的诊断和鉴别诊断。
