用于骨修复的纳米支架的最新进展。
Recent advances in nano scaffolds for bone repair.
作者信息
Yi Huan, Ur Rehman Fawad, Zhao Chunqiu, Liu Bin, He Nongyue
机构信息
State Key Laboratory of Bioelectronics (Chien-Shiung Wu Lab), School of Biological Science and Medical Engineering, Southeast University , Nanjing, China.
Department of Biomedical Engineering, School of Basic Medical Sciences, Nanjing Medical University , Nanjing, China.
出版信息
Bone Res. 2016 Dec 13;4:16050. doi: 10.1038/boneres.2016.50. eCollection 2016.
Biomedical applications of nanomaterials are exponentially increasing every year due to analogy to various cell receptors, ligands, structural proteins, and genetic materials (that is, DNA). In bone tissue, nanoscale materials can provide scaffold for excellent tissue repair via mechanical stimulation, releasing of various loaded drugs and mediators, 3D scaffold for cell growth and differentiation of bone marrow stem cells to osteocytes. This review will therefore highlight recent advancements on tissue and nanoscale materials interaction.
由于纳米材料与各种细胞受体、配体、结构蛋白和遗传物质（即DNA）具有相似性，其生物医学应用每年都在呈指数级增长。在骨组织中，纳米级材料可以通过机械刺激、释放各种负载药物和介质，为出色的组织修复提供支架，为骨髓干细胞向骨细胞的生长和分化提供三维支架。因此，本综述将重点介绍组织与纳米级材料相互作用的最新进展。
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