氧氟沙星、二氟沙星、环丙沙星及其他选定抗菌剂对羊种布鲁氏菌的体外比较活性
Comparative in vitro activities of ofloxacin, difloxacin, ciprofloxacin, and other selected antimicrobial agents against Brucella melitensis.
作者信息
Khan M Y, Dizon M, Kiel F W
机构信息
King Fahad National Guard Hospital, Riyadh, Kingdom of Saudi Arabia.
出版信息
Antimicrob Agents Chemother. 1989 Aug;33(8):1409-10. doi: 10.1128/AAC.33.8.1409.
Abstract
The in vitro activities of three quinolones (ofloxacin, difloxacin, and ciprofloxacin) were compared with those of trimethoprim-sulfamethoxazole, streptomycin, tetracycline, and rifampin against 47 Brucella melitensis strains. Ofloxacin was the most active of the test antimicrobial agents. It inhibited 90% of B. melitensis strains at a concentration of 0.02 micrograms/ml.
摘要
将三种喹诺酮类药物（氧氟沙星、二氟沙星和环丙沙星）的体外活性与甲氧苄啶-磺胺甲恶唑、链霉素、四环素和利福平对47株羊种布鲁氏菌的活性进行了比较。氧氟沙星是受试抗菌药物中活性最强的。它在浓度为0.02微克/毫升时能抑制90%的羊种布鲁氏菌菌株。
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