Shi Hong-Zhi, Fan Quan-Chun, Gao Jian-Yi, Liu Jun-Lian, Bai Gui-E, Mi Tao, Zhao Shuang, Liu Yu, Xu Dong, Guo Zhi-Feng, Li Yong-Zhi
State Key Laboratory of Space Medicine Fundamentals and Application, China Astronaut Research and Training Center, Beijing, 100094, China.
Chin J Integr Med. 2017 Aug;23(8):574-580. doi: 10.1007/s11655-016-2539-5. Epub 2016 Dec 27.
To comprehensively evaluate the health status of 6 volunteers from the Mars 500 Project through analyzing their pulse graphs and determining the changes in cardiovascular function, degree of fatigue and autonomic nervous function.
Six volunteers were recruited; all were male aged 26-38 years (average 31.83±4.96 years). Characteristic parameters reflflecting the status of cardiovascular functions were extracted, which included left ventricular contraction, vascular elasticity and peripheral resistance. The degree of fatigue was determined depending on the difference between the calendar age and biological age, which was calculated through the analysis of blood pressure value and characteristic parameters. Based on the values of pulse height variation and pulse time variation on a 30-s pulse graph, autonomic nervous function was evaluated. All parameters examined were marked on an equilateral polygon to form an irregular polygon of the actual fifigure, then health status was evaluated based on the coverage area of the actual fifigure.
The results demonstrated: (1) volunteers developed weakened pulse power, increased vascular tension and peripheral resistance, and slight decreased ventricular systolic function; (2) the degree of fatigue was basically mild or moderate; and (3) autonomic nervous function was excited but generally balanced.
These volunteers were in the state of sub-health. According to Chinese medicine theories, such symptoms are mainly caused by the weakening of healthy qi, Gan (Liver) failing in free coursing, and disharmony between Gan and Wei (Stomach), which manifests as a weak and string-like pulse.
通过分析6名“火星500”项目志愿者的脉象图，测定其心血管功能、疲劳程度及自主神经功能的变化，全面评估他们的健康状况。
招募6名志愿者，均为男性，年龄26 - 38岁（平均31.83±4.96岁）。提取反映心血管功能状态的特征参数，包括左心室收缩功能、血管弹性和外周阻力。根据日历年龄与生物年龄的差值确定疲劳程度，生物年龄通过分析血压值和特征参数计算得出。基于30秒脉象图上的脉高变化值和脉时变化值评估自主神经功能。将所有检测参数标注在等边多边形上，形成实际图形的不规则多边形，然后根据实际图形的覆盖面积评估健康状况。
结果显示：（1）志愿者脉象力量减弱，血管张力和外周阻力增加，心室收缩功能略有下降；（2）疲劳程度基本为轻度或中度；（3）自主神经功能兴奋但总体平衡。
这些志愿者处于亚健康状态。根据中医理论，此类症状主要由正气虚弱、肝失疏泄、肝胃不和所致，表现为脉弱而弦。
