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一例罕见的非典型眼眶孤立性纤维瘤病例。

A Rare Case of An Atypical Solitary Fibrous Tumour of Orbit.

作者信息

Mehta Hetal Mahendra, Ingole Avinash Babarao, Gharat Anuja Mihir, Murade Sujit Mardansingh, Nicholson Anjali Darius

机构信息

Speciality Medical Officer, Department of Ophthalmology, BMC Eye Hospital , Mumbai, Maharashtra, India .

Additional Professor, Department of Ophthalmology, B.Y.L. Nair Ch. Hopsital , Mumbai, Maharashtra, India .

出版信息

J Clin Diagn Res. 2016 Nov;10(11):ND01-ND03. doi: 10.7860/JCDR/2016/21001.8793. Epub 2016 Nov 1.

Abstract

Solitary fibrous tumours are of mesenchymal origin and comprise of uncommon spindle cell neoplasias. Most commonly the lesions arise from pleura but other rarer sites include lungs, peritoneum, pericardium, nasal cavities, thyroid, parotid gland and orbit. We report the case of a 41-year-old male patient who presented to us with a painless, progressive growth of a mass in the superior part of left orbit with proptosis and inferotemporal displacement of the left eye. Computed Tomography (CT) scan revealed homogeneous enhancing lesion in the superior compartment of left orbit in the extraconal region, extending intraconally and distorting the globe. Upon imaging, the differential diagnosis were lacrimal gland tumour, atypical cavernous haemangioma and nerve sheath tumour. Surgical treatment included complete excision of the mass with the intraoperative finding of mass extending upto the superior oblique tendon, a part of which was excised. Histopathological examination revealed CD34 positive, Bcl-2 and MIC-2 positive tumour with the diagnosis of a solitary fibrous tumour with atypical features but no malignant features. After a follow-up of 18 months, no recurrence was detected.

摘要

孤立性纤维性肿瘤起源于间叶组织,由罕见的梭形细胞瘤组成。这些病变最常见于胸膜,但其他较罕见的部位包括肺、腹膜、心包、鼻腔、甲状腺、腮腺和眼眶。我们报告了一例41岁男性患者,他因左眼眶上部出现无痛性、进行性生长的肿块,伴有眼球突出和左眼颞下移位而前来就诊。计算机断层扫描(CT)显示左眼眶锥外区域上部分隔内有均匀强化病变,延伸至锥内并使眼球变形。影像学检查时,鉴别诊断包括泪腺肿瘤、非典型海绵状血管瘤和神经鞘瘤。手术治疗包括完整切除肿块,术中发现肿块延伸至滑车神经肌腱,切除了其中一部分。组织病理学检查显示肿瘤CD34阳性、Bcl-2和MIC-2阳性,诊断为具有非典型特征但无恶性特征的孤立性纤维性肿瘤。随访18个月后,未发现复发。

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本文引用的文献

1
Solitary fibrous tumor of the orbit.眼眶孤立性纤维瘤
Asian J Neurosurg. 2016 Jan-Mar;11(1):78. doi: 10.4103/1793-5482.165804.
4
Solitary fibrous tumor of the orbit with intracranial involvement.眼眶孤立性纤维瘤伴颅内累及。
Ophthalmic Plast Reconstr Surg. 2011 May-Jun;27(3):e74-6. doi: 10.1097/IOP.0b013e3181ed3590.

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