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一种新型眼睑洗发水对睑板腺功能障碍患者眼睑卫生及睫毛长度的影响:一项比较性开放研究

Effects of a New Eyelid Shampoo on Lid Hygiene and Eyelash Length in Patients with Meibomian Gland Dysfunction: A Comparative Open Study.

作者信息

Kobayashi Asuka, Ide Takeshi, Fukumoto Teruki, Miki Emiko, Tsubota Kazuo, Toda Ikuko

机构信息

Minamiaoyama Eye Clinic, Renai Aoyama Building 4F, 3-3-11 Kitaaoyama, Minato-ku, Tokyo 107-0061, Japan.

Minamiaoyama Eye Clinic, Renai Aoyama Building 4F, 3-3-11 Kitaaoyama, Minato-ku, Tokyo 107-0061, Japan; Department of Ophthalmology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 1608582, Japan.

出版信息

J Ophthalmol. 2016;2016:4292570. doi: 10.1155/2016/4292570. Epub 2016 Dec 19.

Abstract

. Meibomian gland dysfunction (MGD) can lead to abnormalities in the composition and function of tear film, resulting in dry eye. Eyelid hygiene is a key to management of MGD. We tested a novel eyelid shampoo (Eye Shampoo Long, ESL) for its ability to maintain lid hygiene. This shampoo is nonirritating and can potentially lengthen eyelashes. This study was aimed to evaluate the efficacy of ESL in the treatment of MGD and its effects on eyelash length. . Ten patients with MGD and 10 healthy subjects without MGD applied ESL twice daily for 8 weeks. Patients were examined for lid margin and dry eye before and after the trial. Subjective symptoms were evaluated. Eyelash length was measured at baseline and at the end of the trial. . In the MGD group, significant improvements were observed in subjective symptoms obstruction of the meibomian orifice, secretion of meibum, eyelashes contamination, eyelid margin foam, and SPK. Eyelash length became significantly longer. . Maintaining eyelid hygiene using ESL improved the eyelid margins and symptoms of dry eye in MGD patients and increased eyelash length. These findings are promising and warrant confirmation in a larger randomized controlled study.

摘要

睑板腺功能障碍(MGD)可导致泪膜成分和功能异常,从而引发干眼。眼睑卫生是MGD管理的关键。我们测试了一种新型眼睑洗发水(长效眼部洗发水,ESL)维持眼睑卫生的能力。这种洗发水无刺激性,还可能使睫毛变长。本研究旨在评估ESL治疗MGD的疗效及其对睫毛长度的影响。10例MGD患者和10例无MGD的健康受试者每天使用ESL两次,持续8周。在试验前后对患者进行睑缘和干眼检查。评估主观症状。在基线和试验结束时测量睫毛长度。在MGD组中,睑板腺开口阻塞、睑脂分泌、睫毛污染、睑缘泡沫和点状上皮糜烂等主观症状有显著改善。睫毛长度显著变长。使用ESL维持眼睑卫生可改善MGD患者的睑缘和干眼症状,并增加睫毛长度。这些发现很有前景,需要在更大规模的随机对照研究中得到证实。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd7d/5204100/9f18e30e4fee/JOPH2016-4292570.001.jpg

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