Institute of Chemistry, The Center for Nanoscience and Nanotechnology, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.
Nanoscale. 2017 Jan 26;9(4):1416-1422. doi: 10.1039/c6nr08209b.
Dimer- and trimer-origami frames are bridged by duplexes that include caged, sequence-specific, anti-ATP and/or anti-cocaine aptamer sequences. The programmed dissociation of the origami dimers or trimers in the presence of ATP and/or cocaine ligands is demonstrated. The processes are followed by AFM imaging and by electrophoretic experiments.
二聚体和三聚体折纸框架由包含笼形、序列特异性、抗 ATP 和/或抗可卡因适体序列的双链体桥接。证明了在 ATP 和/或可卡因配体存在下折纸二聚体或三聚体的程序化解离。通过原子力显微镜成像和电泳实验来跟踪这些过程。
