Department of Preventive Medicine and Public Health, University of Navarra, Pamplona, Spain;
Navarra's Health Research Institute (IDISNA), Pamplona, Spain.
Adv Nutr. 2017 Jan 17;8(1):146S-154S. doi: 10.3945/an.115.011536. Print 2017 Jan.
The role of yogurt consumption in the risk of developing overweight, obesity, or metabolic syndrome has been the subject of epidemiologic studies over the last 10 y. A comprehensive literature search on MEDLINE and ISI Web of Knowledge from 1966 through June 2016 was conducted to examine the relation between yogurt consumption and weight gain, as well as the risk of overweight, obesity, or metabolic syndrome, in prospective cohort studies. Ten articles met all the inclusion criteria and were included in our systematic review. Of the 10 cohort studies, 3 analyzed the relation between yogurt consumption and the risk of overweight or obesity, 8 analyzed changes in waist circumference or weight changes, 3 studied the association with the risk of developing metabolic syndrome, and 1 studied the probability of abdominal obesity reversion. Although an inverse association between yogurt consumption and the risk of developing overweight or obesity was not fully consistent or always statistically significant, all studies but one showed in their point estimates inverse associations between yogurt consumption and changes in waist circumference, changes in weight, risk of overweight or obesity, and risk of metabolic syndrome during follow-up, although not all estimates were statistically significant (2 studies). Prospective cohort studies consistently suggested that yogurt consumption may contribute to a reduction in adiposity indexes and the risk of metabolic syndrome. Therefore, there is a need for more prospective studies and high-quality randomized clinical trials to confirm this apparent inverse association.
酸奶摄入与超重、肥胖或代谢综合征风险之间的关系一直是过去 10 年来流行病学研究的主题。对 MEDLINE 和 ISI Web of Knowledge 进行了全面的文献检索,检索时间为 1966 年至 2016 年 6 月,以研究酸奶摄入与体重增加以及超重、肥胖或代谢综合征风险之间的关系。符合所有纳入标准的文章有 10 篇,被纳入我们的系统评价。在这 10 项队列研究中,有 3 项分析了酸奶摄入与超重或肥胖风险之间的关系,8 项分析了腰围变化或体重变化,3 项研究了与代谢综合征风险的关联,1 项研究了腹部肥胖逆转的可能性。虽然酸奶摄入与超重或肥胖风险之间的反比关系并不完全一致或始终具有统计学意义,但除了一项研究外,所有研究的点估计值都表明,在随访期间,酸奶摄入与腰围变化、体重变化、超重或肥胖风险以及代谢综合征风险之间存在反比关系,尽管并非所有估计值均具有统计学意义(2 项研究)。前瞻性队列研究一致表明,酸奶摄入可能有助于减少肥胖指数和代谢综合征的风险。因此,需要更多的前瞻性研究和高质量的随机临床试验来证实这种明显的反比关系。