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一种具有聚集诱导发光特性的双通道响应荧光探针及其在活细胞中超氧阴离子选择性成像中的应用。

A two-channel responsive fluorescent probe with AIE characteristics and its application for selective imaging of superoxide anions in living cells.

作者信息

Gao Xiaoying, Feng Guangxue, Manghnani Purnima Naresh, Hu Fang, Jiang Nan, Liu Jianzhao, Liu Bin, Sun Jing Zhi, Tang Ben Zhong

机构信息

MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China.

出版信息

Chem Commun (Camb). 2017 Feb 4;53(10):1653-1656. doi: 10.1039/c6cc09307h. Epub 2017 Jan 18.

DOI:10.1039/c6cc09307h
PMID:28098271
Abstract

A two-channel responsive and AIE-active fluorescent probe was developed to selectively detect superoxide anions in living cells, which can be used to track the endogenous superoxide anion level when cells undergo apoptosis and inflammation.

摘要

开发了一种双通道响应且具有聚集诱导发光活性的荧光探针，用于选择性检测活细胞中的超氧阴离子，当细胞发生凋亡和炎症时，该探针可用于追踪内源性超氧阴离子水平。

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